Evidence map›Paper›PMID 34394947›Full record

ArticleCanadian journal of kidney health and disease2021

Impact of Perioperative Complications on Living Kidney Donor Health-Related Quality of Life and Mental Health: Results From a Prospective Cohort Study.

Carlos Garcia-Ochoa, Liane S Feldman, Chris Nguan, Mauricio Monroy-Caudros, Jennifer B Arnold, Lianne Barnieh, Neil Boudville, Meaghan S Cuerden, Christine Dipchand, John S Gill and 9 more

2 registry-linked trialsOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian journal of kidney health and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00319579 completednot on this map

The Long Term Medical and Psychological Implications of Becoming a Living Kidney Donor: A Prospective Pilot Study

TypeobservationalSponsorAmit GargRan2005 to 2009Enrolled330ConditionsLiving Kidney Donors
NCT00936078 completednot on this map

The Living Kidney Donor Safety Study (Long-term Effects of Becoming a Living Kidney Donor)

TypeobservationalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2009 to 2022Enrolled1,438ConditionsLiving Kidney Donation
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 13 institutions in 2 countries.

Carlos Garcia-OchoaLondon Health Sciences Centre, ON, Canada.
Liane S FeldmanDepartment of Surgery, McGill University Health Centre, Montreal, QC, Canada.
Chris NguanThe University of British Columbia, Vancouver, Canada.
Mauricio Monroy-CaudrosFoothills Medical Center, University of Calgary, AB, Canada.
Jennifer B ArnoldLondon Health Sciences Centre, ON, Canada.
Lianne BarniehLondon Health Sciences Centre, ON, Canada.ORCID https://orcid.org/0000-0003-2403-2392
Neil BoudvilleMedical School, Department of Renal Medicine, Sir Charles Gairdner Hospital, The University of Western Australia, Perth, Australia.
Meaghan S CuerdenLondon Health Sciences Centre, ON, Canada.
Christine DipchandDivision of Nephrology, Dalhousie University, Halifax, NS, Canada.
John S GillThe University of British Columbia, Vancouver, Canada.
Martin KarpinskiUniversity of Manitoba, Winnipeg, Canada.
Scott KlarenbachDivision of Nephrology, University of Alberta, Edmonton, Canada.
Greg KnollDivision of Nephrology, Department of Medicine, University of Ottawa, ON, Canada.
Charmaine E LokUniversity of Toronto, ON, Canada.
Matthew MillerDivision of Nephrology and Transplantation, St. Joseph's Healthcare Hamilton, McMaster University, Hamilton, ON, Canada.
G V Ramesh PrasadSt. Michael's Hospital, Toronto, ON, Canada.
Jessica M SontropDepartment of Epidemiology & Biostatistics, Western University, London, ON, Canada.ORCID https://orcid.org/0000-0001-7784-2028
Leroy StorsleyUniversity of Manitoba, Winnipeg, Canada.
Amit X GargDepartment of Epidemiology & Biostatistics, Western University, London, ON, Canada.ORCID https://orcid.org/0000-0003-3398-3114
London Health Sciences Centre · CAUniversity of British Columbia · CAUniversity of Manitoba · CAWestern University · CADalhousie University · CAMcGill University Health Centre · CASt. Joseph’s Healthcare Hamilton · CASt. Michael's Hospital · CAThe University of Western Australia · AUUniversity of Alberta · CAUniversity of Calgary · CAUniversity of Ottawa · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough living kidney donation is safe, some donors experience perioperative complications.

objectiveThis study explored how perioperative complications affected donor-reported health-related quality of life, depression, and anxiety.

designThis research was a conducted as a prospective cohort study.

settingTwelve transplant centers across Canada. PATIENTS: A total of 912 living kidney donors were included in this study. MEASUREMENTS: Short Form 36 health survey, Beck Depression Inventory and Beck Anxiety Inventory.

methodsLiving kidney donors were prospectively enrolled predonation between 2009 to 2014. Donor perioperative complications were graded using the Clavien-Dindo classification system. Mental and physical health-related quality of life was assessed with the 3 measurements; measurements were taken predonation and at 3- and 12-months postdonation.

resultsSeventy-four donors (8%) experienced a perioperative complication; most were minor (n = 67 [91%]), and all minor complications resolved before hospital discharge. The presence (versus absence) of a perioperative complication was associated with lower mental health-related quality of life and higher depression symptoms 3-month postdonation; neither of these differences persisted at 12-month. Perioperative complications were not associated with any changes in physical health-related quality of life or anxiety 3-month postdonation. LIMITATIONS: Minor complications may have been missed and information on complications postdischarge were not collected. No minimal clinically significant change has been defined for kidney donors across the 3 measurements.

conclusionsThese findings highlight a potential opportunity to better support the psychosocial needs of donors who experience perioperative complications in the months following donation.

trial registrationNCT00319579 and NCT00936078.

Indexed as

depressionhealth-related quality of lifeliving kidney donation

Identifiers

PMID34394947
PMCPMC8361543
OpenAlexW3188043980

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.