ArticleJournal of ophthalmic & vision research
Change in the Foveal Avascular Zone and Macular Capillary Network Density after Hyperbaric Oxygen Therapy in Healthy Retina.
Article in Journal of ophthalmic & vision research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Effects of a Hyperbaric Normoxic Environment on the Retina and Choroid.Investigative ophthalmology & visual science · 2025Article
- Impact of a single session of hyperbaric oxygen therapy on the healthy retina.Frontiers in ophthalmology · 2025Article
- Retinal vascular reactivity in carriers of X-linked inherited retinal disease - a study using optical coherence tomography angiography.Frontiers in ophthalmology · 2024Article
- Hyperbaric Oxygen Therapy in Ophthalmology: A Narrative Review.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to evaluate responses in retinal tissue by swept source OCT angiography (OCT-A) to hyperoxia after hyperbaric oxygen (HBO2) therapy.
methodsThe study was conducted in volunteers who received HBO2 treatment but did not have any eye disease. Patients underwent detailed eye examinations including dilated fundus examination, visual acuity, and refraction before being admitted for HBO2 therapy. Measurements were made before and immediately after HBO2 therapy. Enface images of the retinal vasculature were obtained from the superficial and deep retinal plexus (SP/DP). Quantitative analysis of the vessel density (VD) and foveal avascular zone (FAZ) area was performed.
resultsIn total, 31 patients (15 female) with healthy retina were included in the study. The mean age was 42.8 years. The mean SP vascular density measurements before HBO2 therapy for the right and left eyes were 15.18
conclusionThe healthy retina responds to oxygen supersaturation with HBO2 therapy by eventually decreasing vascular density in all layers. These findings may be important for further studies especially related to retina and choroidal oxygenation.
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