Evidence map›Paper›PMID 34394824›Full record

ReviewOxidative medicine and cellular longevity2021

Pharmacological Properties and Health Benefits of Eugenol: A Comprehensive Review.

Muhammad Farrukh Nisar, Mahnoor Khadim, Muhammad Rafiq, Jinyin Chen, Yali Yang, Chunpeng Craig Wan

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
22.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 247 citations in OpenAlex.

  1. Clinical performance of two chemomechanical caries removal agents in primary molars: a randomized controlled trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Muhammad Farrukh NisarJiangxi Key Laboratory for Postharvest Technology and Nondestructive Testing of Fruits & Vegetables, College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China.ORCID https://orcid.org/0000-0001-8873-1227
Mahnoor KhadimDepartment of Physiology and Biochemistry, Cholistan University of Veterinary and Animal Sciences (CUVAS), Bahawalpur 63100, Pakistan.
Muhammad RafiqDepartment of Physiology and Biochemistry, Cholistan University of Veterinary and Animal Sciences (CUVAS), Bahawalpur 63100, Pakistan.ORCID https://orcid.org/0000-0001-9686-6551
Jinyin ChenJiangxi Key Laboratory for Postharvest Technology and Nondestructive Testing of Fruits & Vegetables, College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China.ORCID https://orcid.org/0000-0002-9378-3053
Yali YangDepartment of Pathology, Affiliated Hospital of Yunnan University/Second People's Hospital of Yunnan Province, Kunming 650021, China.ORCID https://orcid.org/0000-0003-4597-2615
Chunpeng Craig WanJiangxi Key Laboratory for Postharvest Technology and Nondestructive Testing of Fruits & Vegetables, College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China.ORCID https://orcid.org/0000-0001-6892-016X
Jiangxi Agricultural University · CNUniversity of Veterinary and Animal Sciences · PKPingxiang University · CNYunnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biologically active phytochemicals are sourced from edible and medicinally important plants and are important molecules being used for the formulation of thousands of drugs. These phytochemicals have great benefits against many ailments particularly the inflammatory diseases or oxidative stress-mediated chronic diseases. Eugenol (EUG) is a versatile naturally occurring molecule as phenolic monoterpenoid and frequently found in essential oils in a wide range of plant species. EUG bears huge industrial applications particularly in pharmaceutics, dentistry, flavoring of foods, agriculture, and cosmeceutics. It is being focused recently due to its great potential in preventing several chronic conditions. The World Health Organization (WHO) has declared EUG as a nonmutant and generally recognized as safe (GRAS) molecule. The available literature about pharmacological activities of EUG shows remarkable anti-inflammatory, antioxidant, analgesic, and antimicrobial properties and has a significant effect on human health. The current manuscript summarizes the pharmacological characteristics of EUG and its potential health benefits.

Indexed as

Anti-Infective AgentsAntineoplastic AgentsAntioxidantsBacteriaCell SurvivalEugenolHumansHypoglycemic AgentsOils, VolatileOxidative StressAnti-Infective AgentsAntineoplastic AgentsAntioxidantsEugenolHypoglycemic AgentsOils, Volatile

Identifiers

PMID34394824
PMCPMC8357497
OpenAlexW3192541918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.