ArticleTherapeutic advances in neurological disorders2021
Detecting myasthenia gravis as a cause of unclear dysphagia with an endoscopic tensilon test.
Article in Therapeutic advances in neurological disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Research hotspots and frontiers in post-stroke dysphagia: a bibliometric analysis study.Frontiers in neurology · 2024Pooled it
- The FEES Dysphagia Index: a bias-resilient continuous score that captures expert clinical judgment in 2,943 neurological inpatients.Journal of neurology · 2026Observational
- Mapping neurogenic dysphagia diagnostics in Germany: accessibility, implementation practices, and barriers to swallowing endoscopy.Neurological research and practice · 2026Article
- Impact of a Neurogenic Dysphagia Outpatient Clinic on Diagnosis, Treatment, and Nutrition.European journal of neurology · 2026Article
- Diagnostic performance and safety of the edrophonium test in myasthenia gravis: a retrospective case-control study.Neurological research and practice · 2026Article
- Classifying neurogenic dysphagia as a movement disorder.Brain : a journal of neurology · 2025Review
- Systematic approach to contextualize findings of flexible endoscopic evaluation of swallowing in neurogenic dysphagia- towards an integrated FEES report.Neurological research and practice · 2024Review
- Costs of post-stroke dysphagia during acute hospitalization from a health-insurance perspective.European stroke journal · 2023Article
- Clinical determinants and neural correlates of presbyphagia in community-dwelling older adults.Frontiers in aging neuroscience · 2022Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe flexible endoscopic evaluation of swallowing-tensilon test (FTT) was developed to diagnose myasthenia gravis (MG) in patients with unclear pharyngeal dysphagia. The purpose of this study was to determine sensitivity and specificity of the FTT and compare its diagnostic validity with that of other diagnostic markers.
methodsIn this single-centre pragmatic clinical cohort study, a total of 100 patients with unclear pharyngeal dysphagia were eligible to undergo FTT. All patients were subjected to FTT and subsequently followed up clinically. FTT was considered positive if a significant improvement of pharyngeal swallowing function could be objectified endoscopically upon administration of edrophonium chloride. In addition, repetitive nerve stimulation test and serum MG antibody analysis were conducted.
resultsAll subjects (mean age 62.5 ± 14.1 years, female 33) underwent FTT without any complications. According to the results of the diagnostic procedures and based on long-term clinical follow-up for at least 3 years, 51 patients were finally diagnosed with MG. The sensitivity and specificity for the FTT was 88.2% and 95.9%, respectively. Application of the Cochran's
conclusionFTT has excellent clinical properties to be used routinely in the assessment of dysphagia with isolated or predominant pharyngeal muscle involvement allowing rapid and accurate diagnosis of MG.
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