Evidence map›Paper›PMID 34394358›Full record

ArticleStem cells international2021

Optimal Pore Size of Honeycomb Polylactic Acid Films for In Vitro Cartilage Formation by Synovial Mesenchymal Stem Cells.

Misaki Yagi, Mitsuru Mizuno, Ryota Fujisawa, Hisako Katano, Kentaro Endo, Nobutake Ozeki, Yuriko Sakamaki, Hideyuki Koga, Ichiro Sekiya

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cells international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Misaki YagiCenter for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, 1-5-45, Bunkyo-ku, Yushima, Tokyo, Japan.
Mitsuru MizunoCenter for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, 1-5-45, Bunkyo-ku, Yushima, Tokyo, Japan.
Ryota FujisawaCenter for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, 1-5-45, Bunkyo-ku, Yushima, Tokyo, Japan.
Hisako KatanoCenter for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, 1-5-45, Bunkyo-ku, Yushima, Tokyo, Japan.
Kentaro EndoCenter for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, 1-5-45, Bunkyo-ku, Yushima, Tokyo, Japan.
Nobutake OzekiCenter for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, 1-5-45, Bunkyo-ku, Yushima, Tokyo, Japan.
Yuriko SakamakiResearch Core, Tokyo Medical and Dental University, Tokyo, Japan.
Hideyuki KogaDepartment of Joint Surgery and Sports Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Ichiro SekiyaCenter for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, 1-5-45, Bunkyo-ku, Yushima, Tokyo, Japan.ORCID https://orcid.org/0000-0002-6331-722X
Tokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTissue engineering of cartilage requires the selection of an appropriate artificial scaffold. Polylactic acid (PLA) honeycomb films are expected to be highly biodegradable and cell adhesive due to their high porosity. The purpose of this study was to determine the optimal pore size of honeycomb PLA films for in vitro cartilage formation using synovial mesenchymal stem cells (MSCs).

methodsSuspensions of human synovial MSCs were plated on PLA films with different pore sizes (no pores, or with 5

resultsThe 5

conclusionsHoneycomb PLA films with 5

Identifiers

PMID34394358
PMCPMC8356005
OpenAlexW3192766405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.