Evidence map›Paper›PMID 34394352›Full record

ReviewJournal of oncology2021

Promoting Prognostic Model Application: A Review Based on Gliomas.

Xisong Liang, Zeyu Wang, Ziyu Dai, Hao Zhang, Quan Cheng, Zhixiong Liu

Abstract readReview
In one paragraph

Review in Journal of oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xisong Liang *Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID https://orcid.org/0000-0001-6056-1609
Zeyu Wang *Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID https://orcid.org/0000-0002-6675-5399
Ziyu DaiDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID https://orcid.org/0000-0003-2855-741X
Hao ZhangDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID https://orcid.org/0000-0002-4582-2556
Quan ChengDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID https://orcid.org/0000-0003-2401-5349
Zhixiong LiuDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID https://orcid.org/0000-0002-0288-6306

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant neoplasms are characterized by poor therapeutic efficacy, high recurrence rate, and extensive metastasis, leading to short survival. Previous methods for grouping prognostic risks are based on anatomic, clinical, and pathological features that exhibit lower distinguishing capability compared with genetic signatures. The update of sequencing techniques and machine learning promotes the genetic panels-based prognostic model development, especially the RNA-panel models. Gliomas harbor the most malignant features and the poorest survival among all tumors. Currently, numerous glioma prognostic models have been reported. We systematically reviewed all 138 machine-learning-based genetic models and proposed novel criteria in assessing their quality. Besides, the biological and clinical significance of some highly overlapped glioma markers in these models were discussed. This study screened out markers with strong prognostic potential and 27 models presenting high quality. Conclusively, we comprehensively reviewed 138 prognostic models combined with glioma genetic panels and presented novel criteria for the development and assessment of clinically important prognostic models. This will guide the genetic models in cancers from laboratory-based research studies to clinical applications and improve glioma patient prognostic management.

Identifiers

PMID34394352
PMCPMC8356003

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.