Evidence map›Paper›PMID 34394297›Full record

ArticleAfrican health sciences2021

COVID-19: sitting is the new smoking; the role of exercise in augmenting the immune system among the elderly.

Olorunfemi Tokunbo, Taiwo Abayomi, Damilare Adekomi, Ibukun Oyeyipo

Abstract read
In one paragraph

Article in African health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Health Support for At-Risk Older Adults during COVID-19.Healthcare (Basel, Switzerland) · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Olorunfemi TokunboDepartment of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, Osun State University, PMB 4494, Osogbo, Osun State, Nigeria.
Taiwo AbayomiDepartment of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, Osun State University, PMB 4494, Osogbo, Osun State, Nigeria.
Damilare AdekomiDepartment of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, Osun State University, PMB 4494, Osogbo, Osun State, Nigeria.
Ibukun OyeyipoDepartment of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, Osun State University, PMB 4494, Osogbo, Osun State, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLike smoking, sedentary lifestyle is an issue of great concern because of its deleterious health challenges and implications. Given the global spread of the new coronavirus (COVID-19), social isolation regulations and laws have been implemented in many countries to contain the spread of the virus and this has caused a drastic shift from the usual physically demanding life to a sedentary lifestyle characterized by significantly reduced physical activities and prolong sitting. METHODS/DATA SOURCE: Human and nonhuman primate literature was examined to compare experimental and clinical modulation of inflammatory cytokines by exercised-induced myokines. DATA SYNTHESIS: Experimental and clinical evidence was used to examine whether exercised-induced myokines can prime the immune system of the elderly population during the COVID-19 pandemic.

conclusionThe immune system changes with advancement in age which increases the likelihood of infectious disease morbidity and mortality in older adults. Several epidemiological studies have also shown that physical inactivity among geriatric population impacts negatively on the immune system. Evidences on the importance of exercise in priming the immune system of elderly individuals could be an effective therapeutic strategy in combating the virus as it may well be a case of "let those with the best immune system win".

Indexed as

ExerciseImmune SystemSedentary BehaviorAgedAged, 80 and overAgingCOVID-19CytokinesHumansPandemicsCytokinesExerciseimmune systemmyokinessedentary lifestyle

Identifiers

PMID34394297
PMCPMC8356589

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.