ArticleAfrican health sciences2021
Association analysis of vitamin D receptor gene polymorphisms in North England population with Type 2 diabetes mellitus.
Article in African health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A plethora of laboratory protocols for vitamin D receptor (VDR) gene variants detection: a systematic review of associations with hypertensive disorders of pregnancy.BMC pregnancy and childbirth · 2025Pooled it
- Effect of vitamin D receptor gene TaqI polymorphism on vitamin D levels and biochemical, inflammatory, and oxidative stress markers in individuals with obesity.Molecular biology reports · 2026Article
- Association of VDR gene polymorphisms with prediabetes and Type 2 diabetes mellitus in a sample of the Iranian population.PloS one · 2026Article
- Association between vitamin D receptor FokI gene polymorphism and risk of type 2 diabetes mellitus in the Ethiopian population.Scientific reports · 2025Article
- Allelic Discrimination of Vitamin D Receptor Polymorphisms and Risk of Type 2 Diabetes Mellitus: A Case-Controlled Study.Healthcare (Basel, Switzerland) · 2023Article
- Non communicable diseases persist despite being overshadowed by Covid-19 globally.African health sciences · 2021Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundNumerous diabetes susceptibility loci, include a region consisting vitamin D receptor gene found in chromosome 12q, have been known using genome wide screens.
aimThe aim of present study is to probe the relationship between polymorphism of vitamin D receptor gene (single nucleotide polymorphisms) and type 2 diabetes mellitus (T2DM). Five hundred T2DM patients and 200 healthy subjects with normal HbA1c (≤ 5.0 %), fasting blood sugar (≤ 120 mg/dL) and random blood sugar (≤ 140 mg/dL) were enrolled. METHOLODGY: The genotypes were found by polymerase chain reaction restriction fragment length polymorphism and DNA sequencing.
resultsrevealed that no considerable differences in frequencies of genotype and allele of the Bsm I and Fok I polymorphisms between healthy and patients in the North England (For Fok I: OR = 1.11, 95% CI: 0.72-1.12; for Bsm I: OR = 1.35, 95% CI: 0.79-1.98).
conclusionIt is recommended that both following polymorphisms of vitamin D receptor gene may not considerably add to the progression of T2DM in the North England.
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