Evidence map›Paper›PMID 34394248›Full record

ArticleAfrican health sciences2020

BRAF

Meryem Kaabouch, Hafsa Chahdi, Naima Azouzi, Mohammed Oukabli, Issam Rharrassi, Adil Boudhas, Hassan Jaddi, Mouna Ababou, Nadia Dakka, Amélie Boichard and 4 more

Open access · diamondAbstract read
In one paragraph

Article in African health sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. CHD4 and NOX4 expression in thyroid tumor tissues.Exploration of targeted anti-tumor therapy · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. BRAFCancer medicine · 2022
    Article
  8. Editor's choice: this December 2020.African health sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 3 countries.

Meryem KaabouchLaboratory of Biology of Human Pathologies "BioPatH", Center for Genomics of Human Pathologies "GenoPatH". Faculty of Science in Rabat. Mohammed V University in Rabat, Morocco.
Hafsa ChahdiAnatomic Pathology and Histology Service, Military Hospital Mohammed V of Rabat, Morocco. Equipe de Recherche en PathologieTumorale. Faculty of Medicine and Pharmacy of Rabat, University Mohammed V of Rabat.
Naima AzouziUMR 8200 CNRS, Institut Gustave Roussy, Villejuif, France.
Mohammed OukabliAnatomic Pathology and Histology Service, Military Hospital Mohammed V of Rabat, Morocco. Equipe de Recherche en PathologieTumorale. Faculty of Medicine and Pharmacy of Rabat, University Mohammed V of Rabat.
Issam RharrassiAnatomic Pathology and Histology Service, Military Hospital Mohammed V of Rabat, Morocco. Equipe de Recherche en PathologieTumorale. Faculty of Medicine and Pharmacy of Rabat, University Mohammed V of Rabat.
Adil BoudhasAnatomic Pathology and Histology Service, Military Hospital Mohammed V of Rabat, Morocco. Equipe de Recherche en PathologieTumorale. Faculty of Medicine and Pharmacy of Rabat, University Mohammed V of Rabat.
Hassan JaddiFaculty of Sciences in Rabat. Centre National de l'Energie, des Sciences et Techniques Nucléaires, Rabat, Morocco.
Mouna AbabouLaboratory of Biology of Human Pathologies "BioPatH", Center for Genomics of Human Pathologies "GenoPatH". Faculty of Science in Rabat. Mohammed V University in Rabat, Morocco.
Nadia DakkaLaboratory of Biology of Human Pathologies "BioPatH", Center for Genomics of Human Pathologies "GenoPatH". Faculty of Science in Rabat. Mohammed V University in Rabat, Morocco.
Amélie BoichardUMR 8200 CNRS, Institut Gustave Roussy, Villejuif, France.
Youssef BakriLaboratory of Biology of Human Pathologies "BioPatH", Center for Genomics of Human Pathologies "GenoPatH". Faculty of Science in Rabat. Mohammed V University in Rabat, Morocco.
Corinne DupuyUMR 8200 CNRS, Institut Gustave Roussy, Villejuif, France.
Abderrahmane Al BouzidiAnatomic Pathology and Histology Service, Military Hospital Mohammed V of Rabat, Morocco. Equipe de Recherche en PathologieTumorale. Faculty of Medicine and Pharmacy of Rabat, University Mohammed V of Rabat.
Rabii Ameziane El HassaniLaboratory of Biology of Human Pathologies "BioPatH", Center for Genomics of Human Pathologies "GenoPatH". Faculty of Science in Rabat. Mohammed V University in Rabat, Morocco.
Mohammed V University · MACentre National de la Recherche Scientifique · FRNational Centre for Nuclear Energy, Science and Technology · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of thyroid cancer is increasing worldwide at an alarming rate. BRAF

objectiveTo our knowledge, there are no reported studies neither from Morocco nor from other Maghreb countries regarding the prevalence of BRAF

methodsIn this Single-Institution retrospective study realized in the Anatomic Pathology and Histology Service in the Military Hospital of Instruction Mohammed V 'HMIMV' in Rabat, we report, using direct genomic sequencing, the assessment of BRAF

resultsWe detected BRAF

conclusionOur finding gives to the international community the first estimated incidence of this oncogene in Morocco showing that this prevalence falls within the range of international trends (30% to 90%) reported in distinct worldwide geographic regions.

Indexed as

Adenocarcinoma, FollicularAdultCarcinoma, Papillary, FollicularDNA Mutational AnalysisDNA, NeoplasmFemaleHumansIncidenceMaleMiddle AgedMoroccoMutationPoint MutationPolymorphism, Restriction Fragment LengthPrevalenceProto-Oncogene Proteins B-rafBRAF protein, humanDNA, NeoplasmProto-Oncogene Proteins B-rafBiomarkerBRAFV600EMoroccoThyroid cancer

Identifiers

PMID34394248
PMCPMC8351865
OpenAlexW3113358022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.