Evidence map›Paper›PMID 34394241›Full record

ArticleAfrican health sciences2020

Acute effects of electronic cigarette smoking on ventricular repolarization in adults.

Vahit Demir, Siho Hidayet, Yaşar Turan, Hüseyin Ede

Open access · diamondAbstract read
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Article in African health sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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  7. Editor's choice: this December 2020.African health sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Vahit DemirDepartment of Cardiology, Medical Faculty of Bozok University, Yozgat, Turkey.
Siho HidayetDepartment of Cardiology, Medical Faculty of Inonu University, Malatya, Turkey.
Yaşar TuranDepartment of Cardiology, Medical Faculty of Bozok University, Yozgat, Turkey.
Hüseyin EdeDepartment of Cardiology, Medical Faculty of Bozok University, Yozgat, Turkey.
Bozok Universitesi · TRInonu University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElectronic cigarette (e-cigarette) use is constantly increasing. However, the association between e-cigarette use and ventricular arrhythmia is unknown. Thus, in this study, we aimed to evaluate the markers of ventricular repolarization such as QT interval, corrected QT (QTc), QT dispersion (QTd), peak-to-end interval of the T wave (Tp-e), corrected Tp-e and Tp-e/QT ratios in e-cigarette users.

methodsThe study population consisted 36 e-cigarette users and 40 healthy subjects. Ventricular repolarization parameters were obtained from 12-lead resting electrocardiogram. Ventricular repolarization parameters of the groups were compared.

resultsBasal demographic and laboratory data were similar in both groups. According to the electrocardiographic parameters, the Tp-e interval, corrected Tp-e, and Tp-e/QT ratio were significantly higher in individuals using e-cigarettes than in control subjects [74.9±6.4 milliseconds (ms) vs. 80.1±4.1ms, <0.001; 82.9±7.5 ms vs. 87.8±6.3 ms, p=0.003; 0.20±0.01 vs. 0.21±0.01, p=0.002; respectively].

conclusionThis is the first study to show the disruption of ventricular repolarization properties in e-cigarette users. E-cigarette use in terms of public health leads to augmentation of transmural dispersion of repolarization, which may be potential indicator of ventricular arrhythmogenesis.

Indexed as

Electronic Nicotine Delivery SystemsAdolescentAdultArrhythmias, CardiacCase-Control StudiesCross-Sectional StudiesEchocardiographyElectrocardiographyFemaleHeart VentriclesHumansMaleMiddle AgedProspective StudiesSmokingTurkeyElectronic cigaretteTp-e intervalTp-e/QT ratioventricular repolarization

Identifiers

PMID34394241
PMCPMC8351847
OpenAlexW3111695533

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.