ArticleAfrican health sciences2020
Developmental outcomes of HIV-exposed infants in a low-income South African context.
Article in African health sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Preliminary Testing of the English Version of the Adolescent Screener for Intelligence and Learning Disabilities (SCIL) Among Adolescents in Nigeria.Journal of intellectual disability research : JIDR · 2026Article
- Developmental outcomes of small infants at a high-risk clinic: A short-term longitudinal study.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2025Article
- Caregivers' perspectives of early developmental tele-assessments in challenging circumstances.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2024Article
- Editor's choice: this December 2020.African health sciences · 2020Article
- Prevalence and Associated Factors of Developmental Delay Among Under-five Children in Sub-saharan African Countries: A Systematic Review and Meta-Analysis.Sage open pediatricsReview
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5 authors.
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Abstract
backgroundEffective HIV transmission prevention strategies have led to a growing population of vulnerable HIV- and antiretroviral-exposed infants in sub-Saharan Africa, however uncertainty exists regarding their development.
objectiveTo determine the developmental outcomes of HIV-exposed (HE) infants in a low-income South African context, when compared to HIV-unexposed (HU) counterparts.
methodsIn this prospective cross-sectional, group comparison study, the development of 41 HE and 40 HU infants (mean age=8.4 months, SD=2.1 months) from a low-income context was assessed. Caregivers were interviewed using the Vineland Adaptive Behavior Scales, Third Edition (Vineland-3) to evaluate infants' development.
resultsMost HE participants had age-appropriate overall development (90.2%;n=37). Some HE participants, however, presented with delays in domains of communication (9.8%;n=4), daily living skills (2.4%;n=1), socialisation (19.5%;n=8), and motor development (7.3%;n=3). HU participants also demonstrated some domain-specific delays, thus delays were present in both groups. No statistically significant between-group differences regarding development were found.
conclusionFindings were reassuring and suggested that HE and HU participants had similar development. Developmental differences may, however, only emerge with age, therefore large-scale longitudinal research is recommended. It is suggested that the entire sample was vulnerable, highlighting the importance of developmental surveillance in low-income contexts, irrespective of HIV and antiretroviral exposure status.
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