Evidence map›Paper›PMID 34394214›Full record

ArticleAfrican health sciences2020

Characteristics and treatment outcomes of HIV infected elderly patients enrolled in Kisii Teaching and Referral Hospital, Kenya.

Benuel Nyagaka, Stanslaus Kiilu Musyoki, Lucy Karani, Anthony Kebira Nyamache

Open access · diamondAbstract readComparative Study
In one paragraph

Article in African health sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.0field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Editor's choice: this December 2020.African health sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Benuel NyagakaSchool of health sciences, Kisii University, P.O Box 408-40200, Kisii, Kenya.
Stanslaus Kiilu MusyokiSchool of health sciences, Kisii University, P.O Box 408-40200, Kisii, Kenya.
Lucy KaraniSchool of health sciences, Kisii University, P.O Box 408-40200, Kisii, Kenya.
Anthony Kebira NyamacheDepartment of Microbiology, School of Pure and Applied Sciences, Kenyatta University, P.O. Box 43844 (00100), Nairobi, Kenya.
Kisii University · KEKenyatta University · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA better understanding of the baseline characteristics of elderly people living with HIV/AIDS (PLWHA) is relevant because the world's HIV population is ageing.

objectivesThis study aimed to evaluate the baseline characteristics of PLWHA aged ≥ 50years at recruitment to HIV/AIDS clinic compared against the viral load (VL) and CD4 count among patients attending Kisii Teaching and Referral Hospital (KTRH), Kenya.

methodsWe retrospectively evaluated temporal inclinations of CD4 levels, viral load change and baseline demographic characteristics in the electronic records at the hospital using a mixed error-component model for 1329 PLWHA attending clinic between January 2008 and December 2019.

resultsFindings showed a significant difference in the comparison between baseline VL and WHO AIDS staging (p=0.026). Overall VL levels decreased over the period significantly by WHO AIDS staging (p<0.0001). Significant difference was observed by gender (p<0.0001), across age groups (p<0.0001) and baseline CD4 counts (p=0.003). There were significant differences in WHO staging by CD4 count >200cell/mm3 (p=0.048) and residence (p=0.001).

conclusionAge, WHO AIDS staging, gender and residence are relevant parameters associated with viral load decline and CD4 count in elderly PLWHA. A noticeable VL suppression was attained confirming possible attainment of VL suppression among PLWHA under clinical care.

Indexed as

AdultAgedAged, 80 and overCD4 Lymphocyte CountCross-Sectional StudiesFemaleHIV InfectionsHospitals, TeachingHumansKenyaMaleMiddle AgedRetrospective StudiesTreatment OutcomeViral LoadHIV infected elderly patientsKisii Teaching and Referral Hospital, Kenya

Identifiers

PMID34394214
PMCPMC8351854
OpenAlexW3113249732

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.