Evidence map›Paper›PMID 34394016›Full record

ArticleFrontiers in microbiology2021

A Stochastic Characterization of Hydrogen Peroxide-Induced Regulated Cell Death in

Leda Giannuzzi, Tomás Lombardo, Iván Juárez, Anabella Aguilera, Guillermo Blanco

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Analysis ofPLOS water · 2023
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Leda GiannuzziCentro de Investigación y Desarrollo en Criotecnología de Alimentos, Consejo Nacional de Investigaciones Científicas y Tecnicas, Universidad Nacional de La Plata, La Plata, Argentina.
Tomás LombardoLaboratory of Immunotoxicology (LaITo), Facultad de Farmacia y Bioquímica, Instituto de Estudios de la Inmunidad Humoral Dr. Ricardo A. Margni (IDEHU) UBA-CONICET, Universidad de Buenos Aires, Buenos Aires, Argentina.
Iván JuárezCentro de Investigación y Desarrollo en Criotecnología de Alimentos, Consejo Nacional de Investigaciones Científicas y Tecnicas, Universidad Nacional de La Plata, La Plata, Argentina.
Anabella AguileraCentre for Ecology and Evolution in Microbial Model Systems (EEMiS), Linnaeus University, Kalmar, Sweden.
Guillermo BlancoLaboratory of Immunotoxicology (LaITo), Facultad de Farmacia y Bioquímica, Instituto de Estudios de la Inmunidad Humoral Dr. Ricardo A. Margni (IDEHU) UBA-CONICET, Universidad de Buenos Aires, Buenos Aires, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulated cell death (RCD) encompasses the activation of cellular pathways that initiate and execute a self-dismissal process. RCD occur over a range of stressors doses that overcome pro-survival cellular pathways, while higher doses cause excessive damage leading to passive accidental cell death (ACD). Hydrogen peroxide (HP) has been proposed as a potential tool to control harmful cyanobacterial blooms, given its capacity to remove cyanobacterial cells and oxidize cyanotoxins. HP is a source of hydroxyl radicals and is expected to induce RCD only within a limited range of concentrations. This property makes this compound very useful to better understand stress-driven RCD. In this work, we analyzed cell death in microcystin-producing

Indexed as

binary logistic functioncell deathcyanobacteriaEC50Microcystisregulated cell death

Identifiers

PMID34394016
PMCPMC8356053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.