Evidence map›Paper›PMID 34393991›Full record

ArticleFrontiers in endocrinology2021

Polymorphisms in Lysyl Oxidase Family Genes Are Associated With Intracranial Aneurysm Susceptibility in a Chinese Population.

Chun Luo, Chongyu Hu, Bingyang Li, Junyu Liu, Liming Hu, Rui Dong, Xin Liao, Jilin Zhou, Lu Xu, Songlin Liu and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Chun LuoDepartment of Epidemiology and Health Statistics, XiangYa School of Public Health, Central South University, Changsha, China.
Chongyu HuDepartment of Neurology, Hunan People's Hospital, Changsha, China.
Bingyang LiDepartment of Epidemiology and Health Statistics, XiangYa School of Public Health, Central South University, Changsha, China.
Junyu LiuDepartment of Neurosurgery, XiangYa Hospital, Central South University, Changsha, China.
Liming HuDepartment of Epidemiology and Health Statistics, XiangYa School of Public Health, Central South University, Changsha, China.
Rui DongDepartment of Epidemiology and Health Statistics, XiangYa School of Public Health, Central South University, Changsha, China.
Xin LiaoDepartment of Epidemiology and Health Statistics, XiangYa School of Public Health, Central South University, Changsha, China.
Jilin ZhouDepartment of Neurosurgery, XiangYa Hospital, Central South University, Changsha, China.
Lu XuDepartment of Neurosurgery, XiangYa Hospital, Central South University, Changsha, China.
Songlin LiuDepartment of Neurosurgery, XiangYa Hospital, Central South University, Changsha, China.
Yifeng LiDepartment of Neurosurgery, XiangYa Hospital, Central South University, Changsha, China.
Dun YuanDepartment of Neurosurgery, XiangYa Hospital, Central South University, Changsha, China.
Weixi JiangDepartment of Neurosurgery, XiangYa Hospital, Central South University, Changsha, China.
Junxia YanDepartment of Epidemiology and Health Statistics, XiangYa School of Public Health, Central South University, Changsha, China.
Central South University · CNXiangya Hospital Central South University · CNHunan Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Intracranial aneurysms (IA) comprise a multifactorial disease with unclear physiological mechanisms. The lysyl oxidase ( Methods: This case-control study included 384 patients with IA and 384 healthy individuals without IA (controls). We genotyped 27 single nucleotide polymorphisms (SNPs) of Results: The result showed that Conclusion:

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideAgedAmino Acid OxidoreductasesAsian PeopleCase-Control StudiesChinaFemaleGenotypeHumansIntracranial AneurysmLinkage DisequilibriumMagnetic Resonance ImagingMaleMiddle AgedMultivariate AnalysisAmino Acid OxidoreductasesLOXL1 protein, humanLOXL2 protein, humanLOXL3 protein, humanLOXL4 protein, humanProtein-Lysine 6-Oxidaseintracranial aneurysmLOX geneLOXL2lysyl oxidase family genespolymorphism

Identifiers

PMID34393991
PMCPMC8355735
OpenAlexW3186115997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.