Evidence map›Paper›PMID 34393982›Full record

ReviewFrontiers in neurology2021

Subclinical Carotid Artery Atherosclerosis and Cognitive Function: A Mini-Review.

Håkon Ihle-Hansen, Hege Ihle-Hansen, Else Charlotte Sandset, Guri Hagberg

Abstract readReview
In one paragraph

Review in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Håkon Ihle-HansenDepartment of Medicine, Bærum Hospital- Vestre Viken Hospital Trust, Drammen, Norway.
Hege Ihle-HansenDepartment of Medicine, Bærum Hospital- Vestre Viken Hospital Trust, Drammen, Norway.
Else Charlotte SandsetOslo Stroke Unit, Department of Neurology, Oslo University Hospital, Ullevål, Norway.
Guri HagbergDepartment of Medicine, Bærum Hospital- Vestre Viken Hospital Trust, Drammen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carotid artery atherosclerosis, the result of a multitude of vascular risk factors, is a promising marker for use in risk stratification. Recent evidence suggests that carotid artery atherosclerosis affects cognitive function and is an independent risk factor for the development of cognitive impairment. Both atherosclerosis and cognitive impairment develop over a prolonged period (years), and due to the aging population, markers to identify persons at risk are needed. Carotid artery atherosclerosis can easily be visualized using non-invasive ultrasound, potentially enabling early and intensified risk factor management to preserve cognitive function or delay further decline. However, the burden of atherosclerosis and temporal exposure required to pose a risk of cognitive impairment is unclear. This mini-review aims to explore the available evidence on the association between carotid atherosclerosis and cognition, and furthermore identify the remaining gaps in knowledge.

Indexed as

carotid artery atherosclerosiscognitive functiondementiaIMTplaque

Identifiers

PMID34393982
PMCPMC8355501

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.