Evidence map›Paper›PMID 34393833›Full record

ArticleFrontiers in physiology2021

Effects of TNFα on Dynamic Cytosolic Ca

Young-Soo Han, Philippe Delmotte, Gary C Sieck

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Molecular mechanisms underlying FCCP-induced mitophagy in human airway smooth muscle cells.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
  2. TNFα-mediated subcellular heterogeneity of succinate dehydrogenase activity in human airway smooth muscle cells.American journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Young-Soo HanDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States.
Philippe DelmotteDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States.
Gary C SieckDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States.
Mayo Clinic in Florida · US

Funding

Impact of Airway Inflammation on MitochondriaR01HL157984 · NHLBI · MAYO CLINIC ROCHESTER · PI PRAKASH, Y. S., SIECK, GARY C. · 2021 to 2024
$2.7M
NHLBI NIH HHS R01 HL157984
6 · The paper itself

Abstract

Previously, we reported that in airway smooth muscle (ASM), the cytosolic Ca

Indexed as

airway smooth muscledynamic Ca2+ sensitivityinflammatory cytokinesmyosin light chainphase-loop plotstemporal delay

Identifiers

PMID34393833
PMCPMC8363307
OpenAlexW3190532244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.