Effects of Lipotoxicity in Brain Microvascular Endothelial Cells During Sirt3 Deficiency-Potential Role in Comorbid Alzheimer's Disease.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

1. Effects of obesity on brain health and cognition.Nature reviews. Neurology · 2026
   Review
2. Long-Chain Fatty Acids as Drivers of Neuroinflammation in Neurodegeneration: Mechanistic Links to Lipid Peroxidation, Ferroptosis, and Mitochondrial Dysfunction.Nutrients · 2026
   Review
3. A systematic review and meta-analysis of the relationship between neuroinflammation and blood-brain barrier based onBiochemistry and biophysics reports · 2026
   Review
4. Therapeutic Potential of Irisin in Neurodegenerative Diseases.International journal of molecular sciences · 2025
   Review
5. The WFS1-ZnT3-ZnAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
   Article
6. Thrombolysis exacerbates cerebrovascular injury after ischemic stroke via a VEGF-B dependent effect on adipose lipolysis.bioRxiv : the preprint server for biology · 2024
   Article
7. Mitochondrial Dysfunction in Endothelial Progenitor Cells: Unraveling Insights from Vascular Endothelial Cells.Biology · 2024
   Review
8. Brain microvascular endothelial cell metabolism and its ties to barrier function.Vitamins and hormones · 2024
   Article
9. The role of SIRT3 in homeostasis and cellular health.Frontiers in cellular neuroscience · 2024
   Review
10. Role of Sirtuin 3 in Degenerative Diseases of the Central Nervous System.Biomolecules · 2023
    Review
11. Exosomal Mir-3613-3p derived from oxygen-glucose deprivation-treated brain microvascular endothelial cell promotes microglial M1 polarization.Cellular & molecular biology letters · 2023
    Article
12. Type 2 Diabetes and Alzheimer's Disease: The Emerging Role of Cellular Lipotoxicity.Biomolecules · 2023
    Review
13. A Promising Strategy to Treat Neurodegenerative Diseases by SIRT3 Activation.International journal of molecular sciences · 2023
    Review
14. Rethinking of Alzheimer's disease: Lysosomal overloading and dietary therapy.Frontiers in aging neuroscience · 2023
    Article
15. Planting conditions can enhance the bioactivity of mulberry by affecting its composition.Frontiers in plant science · 2023
    Article
16. Sirt3 deficiency induced down regulation of insulin degrading enzyme in comorbid Alzheimer's disease with metabolic syndrome.Scientific reports · 2022
    Article
17. Sirtuins functions in central nervous system cells under neurological disorders.Frontiers in physiology · 2022
    Review
18. A Review of ApoE4 Interference Targeting Mitophagy Molecular Pathways for Alzheimer's Disease.Frontiers in aging neuroscience · 2022
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

5 authors at 2 institutions in 1 country.

Funding

Abstract

Indexed as