Evidence map›Paper›PMID 34393660›Full record

ArticleScience and technology of advanced materials2021

Cellular therapy for myocardial ischemia using a temperature-responsive biodegradable injectable polymer system with adipose-derived stem cells.

Yuta Yoshizaki, Hiroki Takai, Nozomi Mayumi, Soichiro Fujiwara, Akinori Kuzuya, Yuichi Ohya

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Science and technology of advanced materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuta YoshizakiOrganization for Research and Development of Innovative Science and Technology (ORDIST), Kansai University, Suita, OsakaJapan.ORCID 0000-0003-0047-2131
Hiroki TakaiFaculty of Chemistry, Materials, Bioengineering, Kansai University, Suita, OsakaJapan.
Nozomi MayumiFaculty of Chemistry, Materials, Bioengineering, Kansai University, Suita, OsakaJapan.
Soichiro FujiwaraFaculty of Chemistry, Materials, Bioengineering, Kansai University, Suita, OsakaJapan.
Akinori KuzuyaFaculty of Chemistry, Materials, Bioengineering, Kansai University, Suita, OsakaJapan.ORCID 0000-0003-0003-2996
Yuichi OhyaFaculty of Chemistry, Materials, Bioengineering, Kansai University, Suita, OsakaJapan.ORCID 0000-0002-8862-850X
Kansai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose-derived stem cell (AdSC) has been attracting attention as a convenient stem cell source. Not only AdSC can differentiate into various tissue cells, but it can also accelerate cell proliferation, anti-inflammation, and angiogenesis by secreting paracrine factors. Studies have demonstrated AdSC treatment of ischemic heart. However, an improvement in the remaining live AdSCs administered at the injected site while maintaining paracrine factor secretion is desired to achieve effective regenerative medicine. We previously reported the ABA-type tri-block copolymer of poly(ɛ-caprolactone-

Indexed as

30 Bio-inspired and biomedical materials; Polymer Materials; Biomaterials; Biomedical applicationAdipose derived stem cellbiodegradable injectable polymercellular therapymyocardial ischemiaparacrine effecttemperature-responsive sol-to-gel transition

Identifiers

PMID34393660
PMCPMC8354160
OpenAlexW3167186349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.