Evidence map›Paper›PMID 34393515›Full record

ArticleCancer management and research2021

Alterations of Signaling Pathways in Essential Thrombocythemia with Calreticulin Mutation.

Wuhan Hui, Wei Zhang, Congyan Liu, Suigui Wan, Wanling Sun, Li Su

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Calreticulin as a marker and therapeutic target for cancer.Clinical and experimental medicine · 2023
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wuhan HuiDepartment of Hematology, Xuan Wu Hospital, Capital Medical University, Beijing, People's Republic of China.
Wei ZhangDepartment of Hematology, Xuan Wu Hospital, Capital Medical University, Beijing, People's Republic of China.
Congyan LiuDepartment of Hematology, Xuan Wu Hospital, Capital Medical University, Beijing, People's Republic of China.
Suigui WanDepartment of Hematology, Xuan Wu Hospital, Capital Medical University, Beijing, People's Republic of China.
Wanling SunDepartment of Hematology, Xuan Wu Hospital, Capital Medical University, Beijing, People's Republic of China.
Li SuDepartment of Hematology, Xuan Wu Hospital, Capital Medical University, Beijing, People's Republic of China.
Xuan Wu Hospital of the Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThough mutations of the calreticulin ( PATIENTS AND

methodsProtein pathway array was performed to analyze the expression levels of proteins involved in various signaling pathways in peripheral blood neutrophils from 18 ET patients with mutated

resultsWe found 20 proteins differentially expressed in ET patients with mutated

conclusionOur study demonstrated that numerous alterations of signaling proteins and pathways in ET patients with mutated

Indexed as

CALRdel52 mutationessential thrombocytosisprotein pathway arraysignaling proteins

Identifiers

PMID34393515
PMCPMC8357313
OpenAlexW3213285361

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.