Evidence map›Paper›PMID 34393504›Full record

ArticleInternational journal of general medicine2021

Development and Validation of Nomogram to Predict Long-Term Prognosis of Critically Ill Patients with Acute Myocardial Infarction.

Yiyang Tang, Qin Chen, Lihuang Zha, Yilu Feng, Xiaofang Zeng, Zhenghui Liu, Famei Li, Zaixin Yu

Abstract read
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Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yiyang TangDepartment of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.ORCID 0000-0002-3441-7918
Qin ChenDepartment of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Lihuang ZhaDepartment of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Yilu FengDepartment of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Xiaofang ZengDepartment of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Zhenghui LiuDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Famei LiDepartment of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Zaixin YuDepartment of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAcute myocardial infarction (AMI) is a common cardiovascular disease with a poor prognosis. The aim of this study was to construct a nomogram for predicting the long-term survival of critically ill patients with AMI. This nomogram will help in assessing disease severity, guiding treatment, and improving prognosis. PATIENTS AND

methodsThe clinical data of patients with AMI were extracted from the MIMIC-III v1.4 database. Cox proportional hazards models were adopted to identify independent prognostic factors. A nomogram for predicting the long-term survival of these patients was developed on the basis of the results of multifactor analysis. The discriminative ability and accuracy of the multifactor analysis were evaluated according to concordance index (C-index) and calibration curves.

resultsA total of 1202 patients were included in the analysis. The patients were randomly divided into a training set (n = 841) and a validation set (n = 361). Multivariate analysis revealed that age, blood urea nitrogen, respiratory rate, hemoglobin, pneumonia, cardiogenic shock, dialysis, and mechanical ventilation, all of which were incorporated into the nomogram, were independent predictive factors of AMI. Moreover, the nomogram exhibited favorable performance in predicting the 4-year survival of patients with AMI. The training set and the validation set had a C-index of 0.789 (95% confidence interval [CI]: 0.765-0.813) and 0.762 (95% CI: 0.725-0.799), respectively.

conclusionThe nomogram constructed herein can accurately predict the long-term survival of critically ill patients with AMI.

Indexed as

acute myocardial infarctionlong-term prognosisMIMIC-IIInomogramretrospective study

Identifiers

PMID34393504
PMCPMC8357623

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