Evidence map›Paper›PMID 34393261›Full record

ArticleGenus2021

Assessing excess mortality in times of pandemics based on principal component analysis of weekly mortality data-the case of COVID-19.

Patrizio Vanella, Ugofilippo Basellini, Berit Lange

Abstract read
In one paragraph

Article in Genus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Review
  10. Assessment of Excess Mortality in Italy in 2020-2021 as a Function of Selected Macro-Factors.International journal of environmental research and public health · 2023
    Article
  11. Article
  12. Article
  13. SARS-CoV-2 Seroprevalence in Germany.Deutsches Arzteblatt international · 2021
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patrizio VanellaDepartment of Epidemiology, Helmholtz Centre for Infection Research (HZI), Inhoffenstr. 7, DE-38124 Brunswick, Germany.ORCID 0000-0002-6736-6774
Ugofilippo BaselliniLaboratory of Digital and Computational Demography, Max Planck Institute for Demographic Research (MPIDR), Konrad-Zuse-Str. 1, DE-18057 Rostock, Germany.
Berit LangeDepartment of Epidemiology, Helmholtz Centre for Infection Research (HZI), Inhoffenstr. 7, DE-38124 Brunswick, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 outbreak has called for renewed attention to the need for sound statistical analyses to monitor mortality patterns and trends over time. Excess mortality has been suggested as the most appropriate indicator to measure the overall burden of the pandemic in terms of mortality. As such, excess mortality has received considerable interest since the outbreak of COVID-19 began. Previous approaches to estimate excess mortality are somewhat limited, as they do not include sufficiently long-term trends, correlations among different demographic and geographic groups, or autocorrelations in the mortality time series. This might lead to biased estimates of excess mortality, as random mortality fluctuations may be misinterpreted as excess mortality. We propose a novel approach that overcomes the named limitations and draws a more realistic picture of excess mortality. Our approach is based on an established forecasting model that is used in demography, namely, the Lee-Carter model. We illustrate our approach by using the weekly age- and sex-specific mortality data for 19 countries and the current COVID-19 pandemic as a case study. Our findings show evidence of considerable excess mortality during 2020 in Europe, which affects different countries, age, and sex groups heterogeneously. Our proposed model can be applied to future pandemics as well as to monitor excess mortality from specific causes of death.

Indexed as

COVID-19 pandemicCross-country mortality trendsDemographyEpidemiologyExcess mortality assessmentMonte Carlo simulationMortality forecastingPrincipal component analysisStochasticityTime series analysis

Identifiers

PMID34393261
PMCPMC8350559

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.