Evidence map›Paper›PMID 34392900›Full record

ArticleRevista portuguesa de cardiologia2021

Cardiac arrhythmias in patients presenting with COVID-19 treated in Portuguese hospitals: A national registry from the Portuguese Association of Arrhythmology, Pacing and Electrophysiology.

Dinis Mesquita, Pedro Carmo, Nuno Cabanelas, Nuno Santos, Vítor Martins, Victor Sanfins, Helena Cristina Costa, José Paulo Fontes, Paulo Fonseca, Leonor Parreira and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Revista portuguesa de cardiologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Cardiovascular System during SARS-CoV-2 Infection.International journal of environmental research and public health · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Atrial inflammation and microvascular thrombogenicity are increased in deceased COVID-19 patients.Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Dinis MesquitaHospital de S. Bernardo, Centro Hospitalar de Setúbal E.P.E., Setúbal, Portugal. Electronic address: dinis.mesquita@gmail.com.
Pedro CarmoHospital de St.ª Cruz, Centro Hospital de Lisboa Ocidental E.P.E., Carnaxide, Portugal; Hospital da Luz, Lisbon, Portugal.
Nuno CabanelasHospital Prof. Doutor Fernando Fonseca E.P.E., Amadora, Portugal.
Nuno SantosHospital Dr. Nélio Mendonça, Funchal, Madeira, Portugal.
Vítor MartinsHospital Distrital de Santarém, E.P.E., Santarém, Portugal.
Victor SanfinsHospital Senhora da Oliveira, E.P.E., Guimarães, Portugal.
Helena Cristina CostaHospital de St.ª Maria, Centro Hospitalar de Lisboa Norte E.P.E., Lisbon, Portugal.
José Paulo FontesHospital de Vila Real, Centro Hospitalar de Trás os Montes e Alto Douro, E.P.E., Portugal.
Paulo FonsecaHospital de Vila Nova de Gaia/Espinho, E.P.E., Portugal.
Leonor ParreiraHospital de S. Bernardo, Centro Hospitalar de Setúbal E.P.E., Setúbal, Portugal; Hospital da Luz, Lisbon, Portugal.
Portuguese Association of Arrhythmology, Pacing and Electrophysiology (APAPE)
Hospital da Luz · PTCentro Hospitalar de Trás os Montes e Alto Douro · PTCentro Hospitalar de Vila Nova de Gaia · PTCentro Hospitalar Lisboa Norte · PTHospital Central do Funchal · PTHospital da Senhora da Oliveira Guimarães · PTHospital de São Bernardo · PTHospital Prof. Dr. Fernando Fonseca · PTInstituto Politécnico de Santarém · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

objectivesIn December 2019, SARS-CoV-2, was discovered as the agent of COVID-19 disease. Cardiac arrhythmias have been reported as frequent but their incidence is unknown. The aim of this research was to assess the real incidence of cardiac arrhythmias among COVID-19 patients admitted to Portuguese hospitals and to understand the underlying prognostic implications.

methodsThe Portuguese Association of Arrhythmology, Pacing and Electrophysiology (APAPE) conducted a survey in Portuguese hospitals to assess the occurrence of arrhythmias in COVID-19 patients, their clinical characteristics, the use of experimental therapies and the impact on QT interval.

resultsTwenty hospitals participated, reporting 692 hospitalized patients. An arrhythmic episode occurred in 81 (11.7%) and 64 (79%) had detailed information on these episodes. New onset arrhythmias occurred in 41 (64%) patients, 45 (70.3%) male, median age 73.5 (61-80.3) years. There were 51 (79.7%) with associated comorbidities, mainly arterial hypertension (41, 64.1%). Of 53 patients (82.3%) on experimental therapy, 7 (10.9%) had an increased QTc interval. Regarding arrhythmias, two patients (3.1%) had ventricular tachycardia, 5 (7.8%) sinus bradycardia, 17 (26.6%) paroxysmal supraventricular tachycardia and 40 (62.5%) atrial fibrillation or flutter. At the time of reporting, there had been no deaths due to arrhythmic syndrome or related complications.

conclusionsIn a population of COVID-19 patients. The incidence of cardiac arrhythmias is high but not associated with increased cardiac mortality although it does though occur frequently in extremely ill patients and with multiple organ failure. Regardless of the use of experimental drugs, the incidence of ventricular arrhythmias is low and atrial fibrillation and other supraventricular arrhythmias are the most prevalent arrythmias.

Indexed as

Atrial FibrillationCOVID-19AgedCardiac ElectrophysiologyHospitalsHumansMalePortugalRegistriesSARS-CoV-2ArritmiasArrythmiasCOVID-19Experimental therapyPortuguesePortuguesesProlongamento QTQT prolongationTerapêutica experimental

Identifiers

PMID34392900
PMCPMC8359673
OpenAlexW4230266165

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.