Observational studyEmerging microbes & infections2021
Maternal CMV seroprevalence rate in early gestation and congenital cytomegalovirus infection in a Chinese population.
Observational study in Emerging microbes & infections, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Pooled it
- Prenatal ultrasound findings associated with intrauterine CMV infection: a multicenter retrospective analysis of clinical and sonographic features.BMC pregnancy and childbirth · 2026Observational
- Article
- Transplacental Transmission of Cytomegalovirus (CMV) in Pregnant Women with Positive Anti-CMV IgG and Negative Anti-CMV IgM in Highly CMV Seropositive Region.Pathogens (Basel, Switzerland) · 2025Article
- The struggles of breastfeeding mothers of preterm infants: a qualitative study.BMC pregnancy and childbirth · 2025Article
- Reinfection With Cytomegalovirus During Pregnancy: A Prospective Cohort Study in Canada.Journal of medical virology · 2025Article
- Health and economic evaluation of cytomegalovirus vaccination strategy among young women in China: a modelling study.BMJ public health · 2025Article
- Congenital CMV infection in a Brazilian neonatal intensive care unit: high prevalence among twin newborns.Virology journal · 2024Article
- Epidemiological characteristics of three herpesviruses infections in children in Nanjing, China, from 2018 to 2023.Frontiers in cellular and infection microbiology · 2024Article
- Vaccine value profile for cytomegalovirus.Vaccine · 2023Article
- Cytomegalovirus seronegativity rate in pregnant women and primary cytomegalovirus infection during pregnancy in rural Germany.BMC pregnancy and childbirth · 2023Article
- Newborn hearing screening program in China: a narrative review of the issues in screening and management.Frontiers in pediatrics · 2023Review
- Excessive IL-15 promotes cytotoxic CD4 + CD28- T cell-mediated renal injury in lupus nephritis.Immunity & ageing : I & A · 2022Article
- The epidemiology and disease burden of congenital TORCH infections among hospitalized children in China: A national cross-sectional study.PLoS neglected tropical diseases · 2022Article
- Analysis of the Results of Cytomegalovirus Testing Combined with Genetic Testing in Children with Congenital Hearing Loss.Journal of clinical medicine · 2022Article
- High Levels of CD244 Rather Than CD160 Associate With CD8Frontiers in immunology · 2022Article
Corrections and comments
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Authors and funding
18 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Congenital human cytomegalovirus (CMV) infection remains largely unrecognized and underemphasized in medical practice. This study aimed to describe the maternal CMV seroprevalence rate in early gestation and congenital CMV infection in a Chinese population. Methods This prospective cohort study was conducted in three hospitals in China from 2015 through 2018. Pregnant women were enrolled in early gestation and followed up in middle and late gestation with serological testing. CMV serostatus was determined by IgG testing in serum during early gestation. Their newborns were screened for cCMV infection by PCR testing in both saliva and urine at two time points. The cCMV prevalence, maternal seroprevalence and associated factors were analyzed. Results In China, the CMV seroprevalence was 98.11% (6602/6729, 95% CI: 97.76%-98.41%), and the cCMV prevalence was 1.32% (84/6350, 95% CI: 1.07%-1.64%). Over 98% of cCMV-positive newborns were from pregnant women who were seropositive in early gestation in China. The prevalence of cCMV infection in newborns from seropositive and seronegative pregnant women was similar (crude prevalence: 1.33% vs 0.82%,
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Registered trials
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