Trial reportTrends in psychiatry and psychotherapy
Efficacy of acceptance and commitment therapy (ACT) on depression, pain acceptance, and psychological flexibility in married women with breast cancer: a pre- and post-test clinical trial.
Trial report in Trends in psychiatry and psychotherapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Acceptance and commitment therapy reduces psychological distress in patients with cancer: a systematic review and meta-analysis of randomized controlled trials.Frontiers in psychology · 2023Pooled it
- Feasibility of an ACT-based group intervention for Malaysian breast cancer survivors with chronic pain.Frontiers in psychology · 2025Trial
- Sexual health counseling improves the sexual satisfaction of breast cancer survivors: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Trial
- Acceptance and Commitment Therapy for Addressing Chronic Cancer Pain: A Narrative Review with Considerations for Utilization in Primary Care.Healthcare (Basel, Switzerland) · 2026Review
- Multidimensional Recovery Trajectories Throughout Breast Cancer Treatment and Survivorship: A Prospective Longitudinal Study.Current oncology (Toronto, Ont.) · 2026Article
- Parallel mediation of psychological flexibility and vulnerability between multiple-screen addiction and mental health outcomes in adolescents.BMC psychology · 2026Article
- The Effect of ACT on Experiential Avoidance and Pain Acceptance: A Study on Women with Myofascial Pain Syndrome.Journal of pain research · 2026Article
- The mediating role of psychological flexibility in the relationship between adverse childhood experiences and symptoms of depression, anxiety, and stress among Vietnamese college students.Discover mental health · 2025Article
- The role of psychological flexibility in relation to health outcomes in people in remission from cancer.British journal of health psychology · 2025Article
- Chatbot-Based Version of a World Health Organization-Validated Intervention for Stress Management in Patients With Breast Cancer (Self-Help Plus): Protocol for a Pilot Feasibility Study.JMIR research protocols · 2025Article
- Demographic and clinical predictors of treatment outcomes in invasive lobular carcinoma breast cancer: insights from Cox regression analysis.Discover oncology · 2025Article
- World Health Organization Evidence-Based Self-Help Plus Intervention for Stress Management via Chatbot: Protocol for Adaptation to a Tech-Enabled Model.JMIR research protocols · 2025Article
- Non-Pharmacological Interventions for Managing the Symptoms of Depression in Women with Breast Cancer: A Literature Review of Clinical Trials.Diseases (Basel, Switzerland) · 2025Review
- Efficacy of acceptance and commitment therapy on psychological rehabilitation in cancer patients treated with proton and heavy ion therapy: a non-randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- iACT4IBD: a randomised controlled trial of a brief online intervention based on acceptance and commitment therapy to improve wellbeing for adults with inflammatory bowel disease.Frontiers in digital health · 2025Article
- A Chatbot-Based Version of the World Health Organization-Validated Self-Help Plus Intervention for Stress Management: Co-Design and Usability Testing.JMIR human factors · 2024Article
- Gender Socialization as a Predictor of Psychosocial Well-Being in Young Women with Breast Cancer.Current oncology (Toronto, Ont.) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveBreast cancer is the most common cancer in women worldwide. Many of these patients suffer from multiple psychological symptoms. The present study aimed to investigate the impact of acceptance and commitment therapy (ACT) on depression, pain acceptance, and psychological flexibility in married women with breast cancer.
methodsThe present study was a pre- and post-test clinical trial with intervention and control groups. The research population consisted of women with breast cancer referred to the Ayatollah Yasrebi and Shahid Beheshti Hospitals in Kashan in 2018. Through a purposive sampling method, 40 women were selected and randomly divided into two groups, namely, intervention (n = 20) and control (n = 20). The applied tools included the Depression, Anxiety and Stress Scale (DASS-21), Chronic Pain Acceptance Questionnaire 8 (CPAQ-8), and Acceptance and Action Questionnaire - II (AAQ-II). Data were analyzed by SPSS 16 using descriptive statistics and analysis of variance (ANOVA).
resultsThe results showed that ACT treatment significantly reduced the mean scores of depression compared to the control group (F = 107.72, p < 0.001). The mean scores of pain acceptance (F = 9.58, p < 0.05) and psychological flexibility (F = 10.61, p < 0 .05) significantly increased in comparison with the control group.
conclusionACT can be considered as an effective therapeutic approach to reduce depression and increase pain acceptance and psychological flexibility in women with breast cancer. These changes appear to be due to improved acceptance of thoughts and feelings associated with cancer and increased psychological flexibility, which is the primary goal of ACT treatment. CLINICAL
trial registrationIranian Registry of Clinical Trials (IRCT), IRCT20190518043620N1.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.