Evidence map›Paper›PMID 34392353›Full record

ReviewEuropean heart journal2021

Artificial intelligence in the diagnosis and management of arrhythmias.

Venkat D Nagarajan, Su-Lin Lee, Jan-Lukas Robertus, Christoph A Nienaber, Natalia A Trayanova, Sabine Ernst

Open access · bronzeAbstract readReview
In one paragraph

Review in European heart journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 124 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Efficacy and safety of ventricular tachycardia ablation versus antiarrhythmics in ischemic cardiomyopathy: a network meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. The use of cardiac imaging in patients undergoing atrial fibrillation ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Review
  14. Article
  15. Review
  16. Article
  17. EHRA perspective on the digital data revolution in arrhythmia management: insights from the association's annual summit.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Review
  18. Artificial intelligence-powered advancements in atrial fibrillation diagnostics: a systematic review.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
  19. Review
  20. Computational modelling of biological systems now and then: revisiting tools and visions from the beginning of the century.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Venkat D NagarajanDepartment of Cardiology, Royal Brompton and Harefield NHS Foundation Trust, Sydney Street, London SW3 6NP, UK.ORCID 0000-0002-7975-2234
Su-Lin LeeWellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS), UCL, Foley Street, London W1W 7TS, UK.ORCID 0000-0002-7841-9106
Jan-Lukas RobertusDepartment of Pathology, Royal Brompton and Harefield NHS Foundation Trust, Sydney Street, London SW3 6NP, UK.
Christoph A NienaberDepartment of Cardiology, Royal Brompton and Harefield NHS Foundation Trust, Sydney Street, London SW3 6NP, UK.
Natalia A TrayanovaDepartment of Biomedical Engineering, Johns Hopkins University, Charles Street, Baltimore, MD 21218, USA.
Sabine ErnstDepartment of Cardiology, Royal Brompton and Harefield NHS Foundation Trust, Sydney Street, London SW3 6NP, UK.ORCID 0000-0003-1258-2477
Royal Brompton & Harefield NHS Foundation Trust · GBJohns Hopkins University · USWellcome / EPSRC Centre for Interventional and Surgical Sciences · GB

Funding

Infarct-related Ventricular Tachycardia Mechanisms: From Micro to ClinicalR01HL142496 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI TRAYANOVA, NATALIA A. · 2019 to 2022
$3.1M
NHLBI NIH HHS R01 HL142496
6 · The paper itself

Abstract

The field of cardiac electrophysiology (EP) had adopted simple artificial intelligence (AI) methodologies for decades. Recent renewed interest in deep learning techniques has opened new frontiers in electrocardiography analysis including signature identification of diseased states. Artificial intelligence advances coupled with simultaneous rapid growth in computational power, sensor technology, and availability of web-based platforms have seen the rapid growth of AI-aided applications and big data research. Changing lifestyles with an expansion of the concept of internet of things and advancements in telecommunication technology have opened doors to population-based detection of atrial fibrillation in ways, which were previously unimaginable. Artificial intelligence-aided advances in 3D cardiac imaging heralded the concept of virtual hearts and the simulation of cardiac arrhythmias. Robotics, completely non-invasive ablation therapy, and the concept of extended realities show promise to revolutionize the future of EP. In this review, we discuss the impact of AI and recent technological advances in all aspects of arrhythmia care.

Indexed as

Artificial IntelligenceAtrial FibrillationBig DataElectrocardiographyHumansAblationArtificial intelligenceAtrial fibrillationElectrophysiologyMachine learning

Identifiers

PMID34392353
PMCPMC8497074
OpenAlexW3193524644

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.