ArticleThe Science of the total environment2021
SARS-CoV-2 concentrations in a wastewater collection system indicated potential COVID-19 hotspots at the zip code level.
Article in The Science of the total environment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Performance and suitability of wastewater based-surveillance for SARS-CoV-2 RNA in public schools.Scientific reports · 2025Article
- Identifying spatiotemporal trends of SARS-CoV-2 RNA in wastewater: from the perspective of upstream and downstream wastewater-based epidemiology (WBE).Environmental science and pollution research international · 2024Article
- Structured Ethical Review for Wastewater-Based Testing in Support of Public Health.Environmental science & technology · 2023Article
- Structured Ethical Review for Wastewater-Based Testing.medRxiv : the preprint server for health sciences · 2023Article
- Surveillance of SARS-CoV-2 in sewage from buildings housing residents with different vulnerability levels.The Science of the total environment · 2023Article
- When case reporting becomes untenable: Can sewer networks tell us where COVID-19 transmission occurs?Water research · 2023Article
- Application of neighborhood-scale wastewater-based epidemiology in low COVID-19 incidence situations.The Science of the total environment · 2022Article
- Optimal allocation and operation of sewer monitoring sites for wastewater-based disease surveillance: A methodological proposal.Journal of environmental management · 2022Article
- Longitudinal SARS-CoV-2 RNA wastewater monitoring across a range of scales correlates with total and regional COVID-19 burden in a well-defined urban population.Water research · 2022Article
- Higher incidence of novel coronavirus (COVID-19) cases in areas with combined sewer systems, heavy precipitation, and high percentages of impervious surfaces.The Science of the total environment · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wastewater based epidemiology (WBE) has been successfully applied for SARS-CoV-2 surveillance at the city and building levels. However, sampling at the city level does not provide sufficient spatial granularity to identify COVID-19 hotspots, while data from building-level sampling are too narrow in scope for broader public health application. The objective of this study was to examine the feasibility of using wastewater from wastewater collection systems (WCSs) to monitor COVID-19 hotspots at the zip code level. In this study, 24-h composite wastewater samples were collected from five manholes and two wastewater treatment plants (WWTPs) in the City of Lincoln, Nebraska. By comparing to the reported weekly COVID-19 case numbers, we identified different hotspots responsible for two COVID-19 surges during the study period. One zip code was the only sampling locations that was consistently tested positive during the first COVID-19 surge. In comparison, nearly all the zip codes tested exhibited virus concentration increases that overlapped with the second COVID-19 surge, suggesting broader spread of the virus at that time. These findings demonstrate the feasibility of using WBE to monitor COVID-19 at the zip code level. Highly localized disease surveillance methods can improve public health prevention and mitigation measures at the community level.
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