Evidence map›Paper›PMID 34391665›Full record

ArticleTrends in parasitology2021

There and back again: malaria parasite single-cell transcriptomics comes full circle.

Christopher Nötzel, Björn F C Kafsack

Abstract readComment
In one paragraph

Article in Trends in parasitology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Novel systems to study vector-pathogen interactions in malaria.Frontiers in cellular and infection microbiology · 2023
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Christopher NötzelDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA; Biochemistry, Cell and Molecular Biology Graduate Program, Weill Cornell Medicine, New York, NY, USA.
Björn F C KafsackDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA. Electronic address: bjk2007@med.cornell.edu.

Funding

Mechanisms of environmental sensing and responses by malaria parasitesR01AI138499 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI DEITSCH, KIRK W · 2018 to 2022
$3.7M
Regulation of Sexual Differentiation in Malaria ParasitesR01AI141965 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI KAFSACK, BJORN FELIX CAESAR · 2019 to 2023
$2.8M
NIAID NIH HHS R01 AI138499NIAID NIH HHS R01 AI141965
6 · The paper itself

Abstract

The Malaria Cell Atlas (MCA) is an ambitious, ongoing project to profile the intensity and heterogeneity of gene expression throughout the entire malaria parasite life cycle with single-cell resolution. Real et al. now complete the cycle by adding the transmission stages of the most virulent malaria parasite, Plasmodium falciparum, to this easy-to-use resource.

Indexed as

MalariaParasitesAnimalsPlasmodium falciparumTranscriptomecell atlasmalariaparasitescRNA-seqsingle-cell transcriptomics

Identifiers

PMID34391665
PMCPMC9623594

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.