Evidence map›Paper›PMID 34390949›Full record

ArticleClinical biomechanics (Bristol, Avon)2021

Ligament deformation patterns of the craniocervical junction during head axial rotation tracked by biplane fluoroscopes.

Chaochao Zhou, Runsheng Guo, Cong Wang, Tsung-Yuan Tsai, Yan Yu, Wei Wang, Guoan Li, Thomas Cha

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Chaochao ZhouOrthopaedic Bioengineering Research Center, Department of Orthopaedic Surgery, Newton-Wellesley Hospital, Newton, MA, USA; Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Runsheng GuoOrthopaedic Bioengineering Research Center, Department of Orthopaedic Surgery, Newton-Wellesley Hospital, Newton, MA, USA; Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Orthopaedics, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Cong WangSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Tsung-Yuan TsaiSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Yan YuDepartment of Spine Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Wei WangOrthopaedic Bioengineering Research Center, Department of Orthopaedic Surgery, Newton-Wellesley Hospital, Newton, MA, USA; Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
Guoan LiOrthopaedic Bioengineering Research Center, Department of Orthopaedic Surgery, Newton-Wellesley Hospital, Newton, MA, USA. Electronic address: gli1@partners.org.
Thomas ChaOrthopaedic Bioengineering Research Center, Department of Orthopaedic Surgery, Newton-Wellesley Hospital, Newton, MA, USA; Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Newton Wellesley Hospital · USShanghai Jiao Tong University · CNHarvard University · USMassachusetts General Hospital · USTongji University · CN

Funding

Evaluating adjacent segment biomechanics after ACDF or TDR surgery in cervical spondylosis patients.R03AG056897 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI CHA, THOMAS D · 2018 to 2019
$128k
NIA NIH HHS R03 AG056897
6 · The paper itself

Abstract

backgroundFrequently, treatment decisions for craniocervical injuries and instability are based on imaging findings, but in vivo ligament kinematics were poorly understood. This study was to determine in vivo deformation patterns of primary ligaments in the craniocervical junction (i.e., C0-2), including the cruciform ligament, alar ligaments, and accessory ligaments, during dynamic head axial rotation.

methodsThe skulls and cervical spines of eight asymptomatic female subjects were dynamically imaged using a biplane fluoroscopic imaging system, when they performed left and right head axial rotations. Using a 3D-to-2D registration technique, the in vivo positions and orientations of cervical segments were determined. An optimization algorithm was implemented to determine ligament wrapping paths, and the resulting ligament deformations were represented by percent elongations. Using paired t-tests, ligament deformations in the end-range position were compared to those in the neutral position.

findingsNo significant differences were observed in segmental motions during left and right head rotations (p > 0.05). In general, slight deformations occurred in each component of the cruciform ligament. For the alar ligaments, the ipsilateral ligament was lengthened from -0.7 ± 13.8% to 16.6 ± 15.7% (p < 0.001*). For the accessory ligaments, the contralateral ligament was lengthened from -2.9 ± 7.5% to 10.1 ± 6.2% (p < 0.001*).

interpretationThis study reveals that there are distinct deformation patterns in craniocervical junction ligaments during dynamic axial head rotation. These ligament deformation data can enhance our understanding of the synergic function of craniocervical junction ligaments, and guide the treatment of craniocervical instability.

Indexed as

Cervical VertebraeLigaments, ArticularBiomechanical PhenomenaFemaleHumansNeckRange of Motion, ArticularBiplane fluoroscopic imagingCraniocervical junctionHead axial rotationIn vivoLigament deformationsSegmental motion

Identifiers

PMID34390949
PMCPMC8490296
OpenAlexW3191787623

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.