ArticleEnvironmental research2022
Associations of hair dye and relaxer use with breast tumor clinicopathologic features: Findings from the Women's circle of Health Study.
Article in Environmental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 30 citations in OpenAlex.
- Analyzing the landscape of "clean" products for textured hair at a Los Angeles Target.Journal of exposure science & environmental epidemiology · 2026Article
- Chemicals of Concern in Chemical Hair Straightening Products: A Scoping Review.Current environmental health reports · 2026Article
- Occupational exposures among hairdressers and the occurrence of hormone-related conditions.Occupational and environmental medicine · 2026Article
- Cosmetic Habits Associated With Breast Cancer in Benin: A Multicenter Case-Control Study.Journal of cosmetic dermatology · 2026Article
- A prospective study of hair dyes and uterine leiomyomata incidence in the study of environment, lifestyle, and fibroids.Fertility and sterility · 2026Article
- Evaluating personal care product use by Environmental Working Group hazard scores in relation to consumers' sociodemographic characteristics, purchasing behaviors, and product safety perceptions.Journal of exposure science & environmental epidemiology · 2025Article
- Feasibility and Acceptability of Assessing Personal Care Product Use and Exposure to Endocrine-Disrupting Chemicals Among Black and Hispanic Breast Cancer Survivors: A Pilot Study.International journal of environmental research and public health · 2025Article
- The Power of Strategic Social Media Influencer Communication to Improve Black Women's Knowledge and Awareness of Environmental Endocrine-Disrupting Chemicals: Surveys of Instagram Users.Journal of medical Internet research · 2025Article
- Validating the Black Identity, Hair Product Use, and Breast Cancer Scale (BHBS) Among Black Breast Cancer Survivors.International journal of environmental research and public health · 2025Article
- Perceived everyday discrimination, socioeconomic status, and mammography behavior.Scientific reports · 2024Article
- Asking Why Is Necessary to Address Health Disparities: A Critical Approach for Solution-Oriented Environmental Epidemiological Research.Environmental health perspectives · 2024Article
- Hair product use and urinary biomarker concentrations of non-persistent endocrine disrupting chemicals among reproductive-aged Black women.Chemosphere · 2024Article
- Hair Dye and Relaxer Use among Cisgender Women in Embu and Nakuru Counties, Kenya: Associations with Perceived Risk of Breast Cancer and Other Health Effects.International journal of environmental research and public health · 2024Article
- Article
- Beauty Beware: Associations between Perceptions of Harm and Safer Hair-Product-Purchasing Behaviors in a Cross-Sectional Study of Adults Affiliated with a University in the Northeast.International journal of environmental research and public health · 2023Article
- Assessment of personal care product use and perceptions of use in a sample of US adults affiliated with a university in the Northeast.Environmental research · 2023Article
- Plasma metabolomics profiles in Black and White participants of the Adventist Health Study-2 cohort.BMC medicine · 2023Article
- Epidemiology and Risk Factors for Breast Cancer: 21st Century Advances, Gaps to Address through Interdisciplinary Science.Cold Spring Harbor perspectives in medicine · 2023Review
- Use of Chemical Hair Straighteners and Fecundability in a North American Preconception Cohort.American journal of epidemiology · 2023Article
- Parabens Promote Protumorigenic Effects in Luminal Breast Cancer Cell Lines With Diverse Genetic Ancestry.Journal of the Endocrine Society · 2023Article
Corrections and comments
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Authors and funding
13 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundBuilding upon our earlier findings of significant associations between hair dye and relaxer use with increased breast cancer risk, we evaluated associations of select characteristics of use with breast tumor clinicopathology.
methodsUsing multivariable-adjusted models we examined the associations of interest in a case-only study of 2998 women with breast cancer, overall and stratified by race and estrogen receptor (ER) status, addressing multiple comparisons using Bonferroni correction.
resultsCompared to salon application of permanent hair dye, home kit and combination application (both salon and home kit application) were associated with increased odds of poorly differentiated tumors in the overall sample. This association was consistent among Black (home kit: OR 2.22, 95 % CI: 1.21-5.00; combination: OR 2.46, 95 % CI: 1.21-5.00), but not White women, and among ER+ (home kit: OR 1.47, 95 % CI: 0.82-2.63; combination: OR 2.98, 95 % CI: 1.62-5.49) but not ER-cases. Combination application of relaxers was associated with increased odds of tumors >2.0 cm vs. <1.0 cm (OR = 1.82, 95 % CI: 1.23-2.69). Longer duration and earlier use of relaxers and combination application of permanent hair dyes and relaxers were associated with breast tumor features including higher tumor grade and larger tumor size, which often denote more aggressive phenotypes, although the findings did not maintain significance with Bonferroni correction.
conclusionsThese novel data support reported associations between hair dye and relaxer use with breast cancer, showing for the first time, associations with breast tumor clinicopathologic features. Improved hair product exposure measurement is essential for fully understanding the impact of these environmental exposure with breast cancer and to guide risk reduction strategies in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.