Evidence map›Paper›PMID 34390682›Full record

ReviewThe American journal of medicine2021

Post-COVID-19 Tachycardia Syndrome: A Distinct Phenotype of Post-Acute COVID-19 Syndrome.

Marcus Ståhlberg, Ulrika Reistam, Artur Fedorowski, Humberto Villacorta, Yu Horiuchi, Jeroen Bax, Bertram Pitt, Simon Matskeplishvili, Thomas F Lüscher, Immo Weichert and 2 more

2 registry-linked trialsOpen access · bronzeAbstract readReview
In one paragraph

Review in The American journal of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 87 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 3 pooled it
34.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05094622 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

Physical Exercise in Patients With Postural Orthostatic Tachycardia Syndrome (POTS) After Covid-19.

TypeinterventionalSponsorKarolinska InstitutetRan2022 to 2025Enrolled30ConditionsCovid19, Post-acute Covid-19 Syndrome, Postural Orthostatic Tachycardia SyndromeArmsPhysical exercise program
NCT05877534 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Effects of Individual Tailored Physical Exercise in Patients With Post COVID-19 Condition, Diagnosed With Postural Orthostatic Tachycardia Syndrome (POTS) - a Randomized Controlled Study

TypeinterventionalSponsorKarolinska InstitutetRan2023 to 2026Enrolled60ConditionsPostural Orthostatic Tachycardia Syndrome, COVID-19, Post COVID-19 Condition, Post-Acute COVID-19 SyndromeArmsIndividual tailored exercise
3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 3 syntheses or guidelines pooled it, 185 citations in OpenAlex.

  1. Guideline
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  12. Targeting the Neonatal Fc Receptor in Autoimmune Diseases: Pipeline and Progress.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2025
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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 9 countries.

Marcus StåhlbergCardiology, Heart, Vascular and Neuro Theme, Karolinska University Hospital and Department of Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address: marcus.stahlberg@ki.se.
Ulrika ReistamCardiology, Heart, Vascular and Neuro Theme, Karolinska University Hospital and Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Artur FedorowskiDepartment of Clinical Sciences, Faculty of Medicine, Lund University, Lund, Sweden; Department of Cardiology, Skåne University Hospital, Malmö, Sweden.
Humberto VillacortaDivision of Cardiology, Fluminense Federal University, Niterói, Rio de Janeiro State, Brazil.
Yu HoriuchiDivision of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan.
Jeroen BaxDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Bertram PittUniversity of Michigan, Ann Arbor.
Simon MatskeplishviliLomonosov Moscow State University Medical Center, Moscow, Russia.
Thomas F LüscherHeart Division, Royal Brompton & Harefield Hospitals and National Heart and Lung Institute, Imperial College, London, UK; Center for Molecular Cardiology, University of Zurich, Switzerland.
Immo WeichertAcute Medicine Department, Ipswich Hospital, East Suffolk and North Essex NHS Foundation Trust, Ipswich, UK.
Khalid Bin ThaniDepartment of Cardiology, Salmaniya Medical Complex, Manama, Bahrain.
Alan MaiselDivision of Cardiovascular Medicine, University of California San Diego, La Jolla.
Karolinska University Hospital · SEEast Suffolk and North Essex NHS Foundation Trust · GBLeiden University Medical Center · NLLomonosov Moscow State University · RULund University · SEMitsui Memorial Hospital · JPSalmaniya Medical Complex · BHUniversidade Federal Fluminense · BRUniversity of California San Diego · USUniversity of Michigan · USUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper we highlight the presence of tachycardia in post-acute COVID-19 syndrome by introducing a new label for this phenomenon-post-COVID-19 tachycardia syndrome-and argue that this constitutes a phenotype or sub-syndrome in post-acute COVID-19 syndrome. We also discuss epidemiology, putative mechanisms, treatment options, and future research directions in this novel clinical syndrome.

Indexed as

Tachycardia, SinusCOVID-19HumansPhenotypePost-Acute COVID-19 SyndromeSARS-CoV-2SyndromeCOVID-19Inappropriate sinus tachycardiaPostural orthostatic tachycardia syndromeTachycardia

Identifiers

PMID34390682
PMCPMC8356730
OpenAlexW3188317265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.