ArticleVeterinary medicine and science2021
Computed tomography may detect liver infiltration of canine diffuse hepatic lymphoma.
Article in Veterinary medicine and science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Triple-phase contrast-enhanced computed tomography findings in dogs with cholangiocarcinoma and combined hepatocellular-cholangiocarcinoma: Pilot study.Open veterinary journal · 2025Article
- Imaging techniques in veterinary medicineEuropean journal of radiology open · 2023Review
- Computed tomography may detect liver infiltration of canine diffuse hepatic lymphoma.Veterinary medicine and science · 2021Article
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Authors and funding
7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundIn dogs, hepatic lymphoma is characterized by neoplastic lymphocyte infiltration into the liver. Reports on the computed tomography (CT) findings of the liver for canine hepatic lymphoma are few, with only one study of multiple liver lesions type.
objectivesThe purpose of this study was to retrospectively assess the CT findings of the liver in canine diffuse hepatic lymphoma.
methodsAs control, five dogs without abnormalities in the liver were included. CT data were analysed, and the following were noted: presence of edge bluntness of the liver, presence of periportal collar sign, the liver size:body weight (BW) ratio and the mean attenuation of liver lesions on pre-contrast, arterial-phase, portal-phase and equilibrium-phase post-contrast images.
resultsOn CT examination, edge bluntness of the liver was significantly detected in lymphoma (4/5, 80%), as opposed to the control (0/5, 0%) (p = 0.048, φ = 0.82). The periportal collar sign was detected in lymphoma (3/5, 60%), as opposed to the control (0/5, 0%) (p = 0.17, φ = 0.65). The liver size:BW ratio of lymphoma cases was significantly higher compared to that of the control cases (p = 0.0002, r = 0.92). The mean Hounsfield unit of lymphoma cases in the pre-contrast, arterial-phase, portal-phase and equilibrium-phase images were significantly lower than in the control cases (p = 0.005, r = 0.81; p = 0.0003, r = 0.91; p = 0.01, r = 0.75 and p = 0.02, r = 0.71, respectively).
conclusionsHepatic lymphoma should be a differential for a blunted and enlarged liver with hypoattenuation on CT examination.
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