ArticleBrain structure & function2022
Broca's area and the search for anatomical asymmetry: commentary and perspectives.
Article in Brain structure & function, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Protracted Functional and Structural Reorganization of Human Prefrontal Cortex Supports Lateralized Category Geometries.bioRxiv : the preprint server for biology · 2026Article
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- Mapping the Cross-species Brain Connectivity Atlas and Hemispheric Asymmetry of the Temporal Pole in Humans and Macaques.Neuroscience bulletin · 2026Article
- Assessment of resting state structural-functional relationships in perisylvian region during the early weeks after birth.Brain structure & function · 2025Article
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- A Self-supervised Deep Learning Model for Diagonal Sulcus Detection with Limited Labeled Data.Neuroinformatics · 2025Article
- Sylvian fissure angle development on fetal MRI: 22-38 gestational weeks.Frontiers in neuroscience · 2025Article
- Review
- Transcutaneous auricular vagus nerve stimulation on upper limb motor function with stroke: a functional near-infrared spectroscopy pilot study.Frontiers in neuroscience · 2023Article
- Asymmetry of brain structure and function: 40 years after Sperry's Nobel Prize.Brain structure & function · 2022Article
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Authors and funding
4 authors.
Funding
Abstract
We present a brief commentary on the field's search for an anatomical asymmetry between Broca's area and its homologue in the non-dominant hemisphere, focusing on a selection of studies, including research from the last decade. We demonstrate that, several years after the influential review of Keller and colleagues from 2009, and despite recent advances in neuroimaging, the existence of a structural asymmetry of Broca's area is still controversial. This is especially the case for studies of the macroanatomy of this region. We point out the inconsistencies in methodology across studies that could account for the discrepancy in results. Investigations of the microstructure of Broca's area show a trend of a leftward asymmetry, but it is still unclear how these results relate to language dominance. We suggest that it may be necessary to combine multiple metrics in a systematic manner to find robust asymmetries and to expand the regional scope of structural investigations. Finally, based on the current state of the literature, we should not rule out the possibility that language dominance may simply not be reflected in local anatomical differences in the brain.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.