Evidence map›Paper›PMID 34390406›Full record

ArticleMetabolomics : Official journal of the Metabolomic Society2021

Beyond relaxed: magnesium chloride anaesthesia alters the circulatory metabolome of a marine mollusc (Perna canaliculus).

Awanis Azizan, Andrea C Alfaro, Tim Young, Leonie Venter

Abstract read
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In one paragraph

Article in Metabolomics : Official journal of the Metabolomic Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Metabolite Changes ofMetabolites · 2023
    Article
  4. What do oysters smell? Electrophysiological evidence that the bivalve osphradium is a chemosensory organ in the oyster, Magallana gigas.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Awanis AzizanAquaculture Biotechnology Research Group, Department of Applied Ecology, School of Science, Auckland University of Technology, Private Bag 92006, Auckland, 1142, New Zealand.
Andrea C AlfaroAquaculture Biotechnology Research Group, Department of Applied Ecology, School of Science, Auckland University of Technology, Private Bag 92006, Auckland, 1142, New Zealand. andrea.alfaro@aut.ac.nz.ORCID http://orcid.org/0000-0003-0543-7212
Tim YoungAquaculture Biotechnology Research Group, Department of Applied Ecology, School of Science, Auckland University of Technology, Private Bag 92006, Auckland, 1142, New Zealand.
Leonie VenterAquaculture Biotechnology Research Group, Department of Applied Ecology, School of Science, Auckland University of Technology, Private Bag 92006, Auckland, 1142, New Zealand.
Auckland University of Technology · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe New Zealand Green-lipped mussel industry is well-established providing vastly to aquaculture exports. To assess mussel health and reproduction status, visual examination of organs and/or collection of haemolymph is commonly applied. Anesthetics, such as magnesium chloride (MgCl

methodsAdult Green-lipped mussels were anaesthetized for 3 h in a MgCl

resultsAnesthetized mussels were characterized as non-responsive to manual manipulation, with open valves, and limited siphoning function. Metabolite profiling revealed significant increases in the abundances of most metabolites with an array of metabolic activities affected, resulting in an energy imbalance driven by anaerobic metabolism with altered amino acids acting as neurotransmitters and osmolytes.

conclusionThis research is the first to use a metabolomics approach to identify the metabolic consequences of this commonly used bivalve relaxing technique. Ultimately the use of MgCl

Indexed as

Calcium Channel BlockersHemolymphMagnesium ChlorideMetabolomePernaAnesthesiaAnestheticsAnimalsGas Chromatography-Mass SpectrometryNeuromuscular AgentsAnestheticsCalcium Channel BlockersMagnesium ChlorideNeuromuscular AgentsAnesthesiaGC–MS metabolomicsGreen-lipped musselMgCl2PhysiologyRelaxant

Identifiers

PMID34390406
OpenAlexW3189561151

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.