ArticleEuropean journal of applied physiology2021
Vagal blockade suppresses the phase I heart rate response but not the phase I cardiac output response at exercise onset in humans.
Article in European journal of applied physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Toward an Understanding of the Psychological Meaning of Physiological Synchrony.Psychophysiology · 2026Review
- Confidence intervals estimator of the kinetic parameters: do its reliability depend on the assembling method of the oxygen uptakes?European journal of applied physiology · 2025Article
- Baroreflex dynamics during the rest to exercise transient in acute normobaric hypoxia in humans.European journal of applied physiology · 2024Article
- Energetics of sinusoidal exercise below and across critical power and the effects of fatigue.European journal of applied physiology · 2024Article
- The algorithm used for the calculation of gas exchange affects the estimation of OExperimental physiology · 2024Article
- Dynamics of cardiovascular and baroreflex readjustments during a light-to-moderate exercise transient in humans.European journal of applied physiology · 2022Article
- A century of exercise physiology: key concepts on coupling respiratory oxygen flow to muscle energy demand during exercise.European journal of applied physiology · 2022Review
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Authors and funding
7 authors.
Funding
Abstract
purposeWe tested the vagal withdrawal concept for heart rate (HR) and cardiac output (CO) kinetics upon moderate exercise onset, by analysing the effects of vagal blockade on cardiovascular kinetics in humans. We hypothesized that, under atropine, the φ
methodsOn nine young non-smoking men, during 0-80 W exercise transients of 5-min duration on the cycle ergometer, preceded by 5-min rest, we continuously recorded HR, CO, SV and oxygen uptake ([Formula: see text]O
resultsIn atropine versus control, A
conclusionThe results are fully compatible with the tested hypothesis. They provide the first direct demonstration that vagal blockade, while suppressing HR φ
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