Evidence map›Paper›PMID 34390348›Full record

ArticleNucleic acids research2022

DRAMP 3.0: an enhanced comprehensive data repository of antimicrobial peptides.

Guobang Shi, Xinyue Kang, Fanyi Dong, Yanchao Liu, Ning Zhu, Yuxuan Hu, Hanmei Xu, Xingzhen Lao, Heng Zheng

Abstract read
In one paragraph

Article in Nucleic acids research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 151 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
151citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

151 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Artificial intelligence catalyzes antimicrobial peptide design.Synthetic and systems biotechnology · 2027
    Review
  3. A MarineMarine drugs · 2026
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  14. De Novo Multi-Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  15. Article
  16. Article
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91 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guobang ShiSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211100, P.R. China.ORCID 0000-0003-2480-9720
Xinyue KangSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211100, P.R. China.
Fanyi DongSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211100, P.R. China.
Yanchao LiuSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211100, P.R. China.
Ning ZhuSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211100, P.R. China.
Yuxuan HuSchool of International Pharmaceutical Business, China Pharmaceutical University, Nanjing 211100, P.R. China.
Hanmei XuThe Engineering Research Centre of Peptide Drug Discovery and Development, China Pharmaceutical University, Nanjing 211100, P.R. China.
Xingzhen LaoSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211100, P.R. China.
Heng ZhengSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211100, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stapled antimicrobial peptides are an emerging class of artificial cyclic peptide molecules which have antimicrobial activity and potent structure stability. We previously published the Data Repository of Antimicrobial Peptides (DRAMP) as a manually annotated and open-access database of antimicrobial peptides (AMPs). In the update of version 3.0, special emphasis was placed on the new development of stapled AMPs, and a subclass of specific AMPs was added to store information on these special chemically modified AMPs. To help design low toxicity AMPs, we also added the cytotoxicity property of AMPs, as well as the expansion of newly discovered AMP data. At present, DRAMP has been expanded and contains 22259 entries (2360 newly added), consisting of 5891 general entries, 16110 patent entries, 77 clinical entries and 181 stapled AMPs. A total of 263 entries have predicted structures, and more than 300 general entries have links to experimentally determined structures in the Protein Data Bank. The update also covers new annotations, statistics, categories, functions and download links. DRAMP is available online at http://dramp.cpu-bioinfor.org/.

Indexed as

SoftwareAmino AcidsAmino Acid SequenceAnimalsAnti-Infective AgentsAntimicrobial PeptidesBacteriaBiomimetic MaterialsDatabases, ProteinErythrocytesHumansImmunologic FactorsInternetMiceMolecular Sequence AnnotationPeptides, CyclicAmino AcidsAnti-Infective AgentsAntimicrobial PeptidesImmunologic FactorsPeptides, Cyclic

Identifiers

PMID34390348
PMCPMC8728287

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.