Evidence map›Paper›PMID 34390115›Full record

ArticleJournal of cellular and molecular medicine2021

Overexpression of bone morphogenetic protein 7 reduces oligodendrocytes loss and promotes functional recovery after spinal cord injury.

Shuxin Liu, Wei Zhang, Lin Yang, Fan Zhou, Peng Liu, Yaping Wang

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shuxin LiuDepartment of Pain Management and Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Wei ZhangDepartment of Pain Management and Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Lin YangDepartment of Pain Management and Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Fan ZhouDepartment of Pain Management and Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Peng LiuDepartment of Disease Prevention and Control, People's Liberation Army Joint Logistic Support Force 921th Hospital, Changsha, China.
Yaping WangDepartment of Pain Management and Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, China.ORCID 0000-0001-6010-095X
Central South University · CN117th Hospital of People's Liberation Army · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal cord injury (SCI), as a severe disease with no effective therapeutic measures, has always been a hot topic for scientists. Bone morphogenetic protein 7 (BMP7), as a multifunctional cytokine, has been reported to exert protective effects on the nervous system. The present study aimed to investigate the neuroprotective effect and the potential mechanisms of BMP7 on rats that suffered SCI. Rat models of SCI were established by the modified Allen

Indexed as

AnimalsBone Morphogenetic Protein 7MaleNeuroprotective AgentsOligodendrogliaRatsRats, Sprague-DawleyRecovery of FunctionSpinal Cord InjuriesBmp7 protein, ratBone Morphogenetic Protein 7Neuroprotective AgentsBMP7demyelinationoligodendrocytesspinal cord injury

Identifiers

PMID34390115
PMCPMC8435414
OpenAlexW3212197868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.