Evidence map›Paper›PMID 34390021›Full record

ArticleMagnetic resonance in medicine2022

Manifold-based respiratory phase estimation enables motion and distortion correction of free-breathing cardiac diffusion tensor MRI.

Jaume Coll-Font, Shi Chen, Robert Eder, Yiling Fang, Qiao Joyce Han, Maaike van den Boomen, David E Sosnovik, Choukri Mekkaoui, Christopher T Nguyen

Open access · bronzeAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jaume Coll-FontCardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0001-9341-6838
Shi ChenCardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Robert EderCardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Yiling FangCardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Qiao Joyce HanCardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Maaike van den BoomenCardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
David E SosnovikCardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Choukri MekkaouiCardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Christopher T NguyenCardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0003-1475-2329
Harvard University · USMassachusetts General Hospital · USUniversity Medical Center Groningen · NL

Funding

Serial evaluation of cardioprotective effects of exercise training in heart failure using cardiac diffusion tensor MRIR01HL151704 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NGUYEN, CHRISTOPHER T · 2020 to 2024
$3.4M
Imaging Histone Deacetylase in the Heart and Bone MarrowR01HL141563 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SOSNOVIK, DAVID E · 2018 to 2021
$3.3M
Microstructural Response of the Myocardium to Mechanical LoadR01HL159010 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MEKKAOUI, CHOUKRI, NGUYEN, CHRISTOPHER T · 2021 to 2024
$3.2M
Stress-rest calf muscle perfusion: a functional diagnostic test for peripheral arterial disease (PAD)R01HL135242 · NHLBI · UNIVERSITY OF UTAH · PI NATARAJAN, PRADEEP · 2017 to 2020
$2.8M
Free-Breathing Diffusion Tensor MRI in Patients Following Myocardial InfarctionR01HL131635 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MEKKAOUI, CHOUKRI · 2016 to 2020
$2.1M
NHLBI NIH HHS R01 HL131635NHLBI NIH HHS R01 HL135242NHLBI NIH HHS R01 HL141563NHLBI NIH HHS R01 HL151704NHLBI NIH HHS R01 HL159010
6 · The paper itself

Abstract

purposeFor in vivo cardiac DTI, breathing motion and B

methodsFree-breathing electrocardiogram-triggered whole left-ventricular cardiac DTI using a second-order motion-compensated spin echo EPI sequence and alternating directionality of phase encoding blips was performed on 11 healthy volunteers. The respiratory phase of each DW image was estimated after projecting the DW images into a 2D space with Laplacian eigenmaps. DisCo and motion compensation were applied to the respiratory sorted DW images. The results were compared against conventional breath-held T

resultsThe left-ventricular geometries after DisCo and motion compensation resulted in significantly improved alignment of DW images with T

conclusionRetrospective respiratory phase estimation with LE-based DisCo and motion compensation in free-breathing cardiac DTI resulting in significantly reduced geometric distortion and improved alignment within and across slices.

Indexed as

Diffusion Magnetic Resonance ImagingDiffusion Tensor ImagingEcho-Planar ImagingHumansMotionReproducibility of ResultsRetrospective Studiescardiac MRIdiffusion tensor imagingdistortion correctionfree-breathingLaplacian eigenmapsmotion compensation

Identifiers

PMID34390021
PMCPMC8616783
OpenAlexW3190691163

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.