Evidence map›Paper›PMID 34389923›Full record

ArticlePharmacoEconomics - open2022

Cost Effectiveness of a Cultural Physical Activity Intervention to Reduce Blood Pressure Among Native Hawaiians with Hypertension.

Ashley F Railey, Clemma Muller, Carolyn Noonan, Maureen Schmitter-Edgecombe, Ka'imi Sinclair, Corin Kim, Mele Look, J Keawe'aimoku Kaholokula

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PharmacoEconomics - open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02620709 (The KaHOLO Project), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02620709 naunknown statusnot on this map

The KaHOLO Project: Preventing Cardiovascular Disease in Native Hawaiians

TypeinterventionalSponsorUniversity of HawaiiRan2016 to 2021Enrolled275ConditionsHypertensionArmsHula intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. The Health Effects of a Cherokee Grounded Culture and Leadership Program.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ashley F RaileyInstitute for Research and Education to Advance Community Health (IREACH), Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA. arailey@iu.edu.ORCID http://orcid.org/0000-0002-0763-5397
Clemma MullerInstitute for Research and Education to Advance Community Health (IREACH), Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA.
Carolyn NoonanInstitute for Research and Education to Advance Community Health (IREACH), Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA.
Maureen Schmitter-EdgecombeDepartment of Psychology, Washington State University, Pullman, WA, USA.
Ka'imi SinclairInstitute for Research and Education to Advance Community Health (IREACH), Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA.
Corin KimKilohana, University of Hawai'i at Hilo, Hilo, HI, USA.
Mele LookDepartment of Native Health, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Mānoa, HI, USA.
J Keawe'aimoku KaholokulaDepartment of Native Health, John A. Burns School of Medicine, University of Hawai'i at Mānoa, Mānoa, HI, USA.
Washington State University Spokane · USUniversity of Hawaiʻi at Mānoa · USUniversity of Hawaii at Hilo · USWashington State University · US

Funding

Tracking and Evaluation CoreU54GM138062 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI KAHOLOKULA, JOSEPH KEAWE'AIMOKU · 2021 to 2025
$15.5M
Res-Ed-ComponentP30AG059295 · NIA · WASHINGTON STATE UNIVERSITY · PI GALVIN, JAMES E, JOHANSSON, PATRIK LENNART · 2018 to 2024
$4.1M
The KaHOLO Project: Preventing Cardiovascular Disease in Native HawaiiansR01HL126577 · NHLBI · UNIVERSITY OF HAWAII AT MANOA · PI KAHOLOKULA, JOSEPH KEAWE'AIMOKU · 2015 to 2019
$3.9M
NHLBI NIH HHS R01 HL126577NHLBI NIH HHS R01HL126577NIA NIH HHS P30 AG059295NIA NIH HHS P30AG059295-01NIGMS NIH HHS U54 GM138062
6 · The paper itself

Abstract

objectiveThe aim of this study was to calculate the costs and assess whether a culturally grounded physical activity intervention offered through community-based organizations is cost effective in reducing blood pressure among Native Hawaiian adults with hypertension.

methodsSix community-based organizations in Hawai'i completed a randomized controlled trial between 2015 and 2019. Overall, 263 Native Hawaiian adults with uncontrolled hypertension (≥ 140 mmHg systolic, ≥ 90 mmHg diastolic) were randomized to either a 12-month intervention group of hula (traditional Hawaiian dance) lessons and self-regulation classes, or to an education-only waitlist control group. The primary outcome was change in systolic blood pressure collected at baseline and 3, 6, and 12 months for the intervention compared with the control group. Incremental cost-effectiveness ratios (ICERs) were calculated for primary and secondary outcomes. Non-parametric bootstrapping and sensitivity analyses evaluated uncertainty in parameters and outcomes.

resultsThe mean intervention cost was US$361/person, and the 6-month ICER was US$103/mmHg reduction in systolic blood pressure and US$95/mmHg in diastolic blood pressure. At 12 months, the intervention group maintained reductions in blood pressure, which exceeded reductions for usual care based on blood pressure outcomes. The change in blood pressure at 12 months resulted in ICERs of US$100/mmHg reduction in systolic blood pressure and US$93/mmHg in diastolic blood pressure. Sensitivity analyses suggested that at the estimated intervention cost, the probability that the program would lower systolic blood pressure by 5 mmHg was 67 and 2.5% at 6 and 12 months, respectively.

conclusionThe 6-month Ola Hou program may be cost effective for low-resource community-based organizations. Maintenance of blood pressure reductions at 6 and 12 months in the intervention group contributed to potential cost effectiveness. Future studies should further evaluate the cost effectiveness of indigenous physical activity programs in similar settings and by modeling lifetime costs and quality-adjusted life-years. TRIAL REGISTRATION NUMBER: NCT02620709.

Identifiers

PMID34389923
PMCPMC8807791
OpenAlexW3193225438

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.