ArticleScientific reports2021
Strong association of type 2 diabetes with degenerative lumbar spine disorders.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- The association between diabetes mellitus and low back pain: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- Is there an association between diabetes and neck and back pain? An updated systematic review with meta-analyses.Chiropractic & manual therapies · 2026Pooled it
- A systematic review and meta-analysis of risk factors for reoperation after degenerative lumbar spondylolisthesis surgery.BMC surgery · 2023Pooled it
- Patients taking GLP-1 agonists for weight-loss prior to posterior lumbar decompression and fusion have similar surgical and patient-reported outcomes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Pattern of Musculoskeletal Pain Among Patients With Type 2 Diabetes: A Cross-Sectional Study.Cureus · 2026Article
- Discordance in bone mineral density between lumbar spine and hip in patients with rheumatoid arthritis: A cross-sectional study.Osteoporosis and sarcopenia · 2026Article
- Diabetic neuropathy is associated with increased long-term morbidity and revision risk following lumbar laminectomy or laminotomy.Journal of spine surgery (Hong Kong) · 2026Article
- Ten-year healthcare utilization patterns among patients with type 2 diabetes and degenerative spinal disorders: a nationwide comparative analysis using nationwide sample.BMC health services research · 2026Article
- Preoperative Clinical and Radiographic Risk Factors for Recurrent Lumbar Disc Herniation: Systematic Review and Meta-analysis.Neurospine · 2026Article
- Clinical and imaging impact of diabetes mellitus on elderly patients with lumbar spinal stenosis: a retrospective propensity score-matched study with ≥5-year follow-up.Frontiers in medicine · 2026Article
- Cellular and molecular mechanisms of diabetes-mediated disc degeneration.Frontiers in endocrinology · 2026Review
- Analysis of the association between lumbar paraspinal muscle atrophy, facet joint degeneration, and degenerative lumbar scoliosis.European journal of medical research · 2025Article
- Impact of diabetes mellitus on spinal injection two-week outcomes in patients with predominant lower extremity pain.Skeletal radiology · 2025Article
- Changes in the Expression Profile of Growth-Associated Protein 43 in Degenerative Lumbosacral Stenosis.Journal of clinical medicine · 2025Article
- Targeting advanced glycation end products: potential therapeutic approaches for mitigating diabetic intervertebral disc degeneration?Frontiers in endocrinology · 2025Review
- Chronic Low Back Pain: History, Symptoms, Pain Mechanisms, and Treatment.Life (Basel, Switzerland) · 2024Review
- Diabetes increases risk of lumbar spinal fusion complications: association with altered structure of newly formed bone at the fusion site.JBMR plus · 2024Article
- The effect of diabetes mellitus on lumbar disc degeneration: an MRI-based study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Machine learning predictive model for lumbar disc reherniation following microsurgical discectomy.Brain & spine · 2024Article
- Effect of Glycemic Disorders and Habits on the Concentration of Selected Neurotrophic Factors in Patients with Lumbosacral Intervertebral Disc Degeneration.Current pharmaceutical biotechnology · 2024Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tantalizing connections between type 2 diabetes and degenerative lumbar spine disorders have become increasingly evident. However, the association of type 2 diabetes with degenerative lumbar spine disorders remains unclear. We sought to clarify the association between type 2 diabetes and lumbar spine disorders using nationwide data in Korea. Furthermore, we explored the association of diabetes with the prevalence of spinal procedures. The data in this study was obtained from Korean health claim database. Between 2016 and 2019, totals of 479,680 diabetes and 479,680 age- and sex-matched control subjects were enrolled. Patients with diabetes had more likely to have degenerative lumbar spine disorders and spinal procedures than controls. Using multivariate-adjusted analysis, patients with diabetes were at increased risk of being concomitantly affected by lumbar disc disorder [adjusted odds ratio 1.11 (95% confidence interval 1.10-1.12)], lumbar spondylotic radiculopathy [1.12 (1.11-1.13)], spondylolisthesis [1.05 (1.02-1.08)] and spinal stenosis [1.16 (1.15-1.18)], compared to controls. Furthermore, diabetic patients had an increased risk of undergoing lumbar spinal injection [1.13 (1.12-1.14)], laminectomy [1.19 (1.15-1.23)], and fusion surgery [1.35 (1.29-1.42)]. We demonstrated that type 2 diabetes was significantly associated with lumbar spine disorders and frequent spinal procedures. Our results suggest diabetes as a predisposing factor for lumbar spine disorders.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.