ArticleNature communications2021
A direct interareal feedback-to-feedforward circuit in primate visual cortex.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- The primate claustrum as a hub for precision weighting of prediction errors across the cortical hierarchy.PLoS biology · 2026Article
- Article
- Prefrontal cortical NR2B-containing NMDA receptors are essential for spatial working memory performance.Translational psychiatry · 2025Article
- Layer-specific spatiotemporal dynamics of feedforward and feedback in human visual object perception.bioRxiv : the preprint server for biology · 2025Article
- Antifragile control systems in neuronal processing: a sensorimotor perspective.Biological cybernetics · 2025Review
- Characterization of depth perception information inferred from neuronal activity in primary visual cortex.PloS one · 2025Article
- Auditory cortex conveys non-topographic sound localization signals to visual cortex.Nature communications · 2024Article
- An optrode array for spatiotemporally-precise large-scale optogenetic stimulation of deep cortical layers in non-human primates.Communications biology · 2024Article
- Cell type-specific connectome predicts distributed working memory activity in the mouse brain.eLife · 2024Article
- Modular horizontal network within mouse primary visual cortex.Frontiers in neuroanatomy · 2024Article
- Cortical circuitry mediating interareal touch signal amplification.Cell reports · 2023Article
- Cellular and laminar architecture: A short history and commentary.The Journal of comparative neurology · 2023Article
- Third-generation rabies viral vectors allow nontoxic retrograde targeting of projection neurons with greatly increased efficiency.Cell reports methods · 2023Article
- Genetic Approaches for Neural Circuits Dissection in Non-human Primates.Neuroscience bulletin · 2023Review
- Review
- Article
- Computational components of visual predictive coding circuitry.Frontiers in neural circuits · 2023Review
- Evaluation of advances in cortical development using model systems.Developmental neurobiology · 2022Review
- The inevitable inequality of cortical columns.Frontiers in systems neuroscience · 2022Article
- Notes on Visual Cortical Feedback and Feedforward Connections.Frontiers in systems neuroscience · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The mammalian sensory neocortex consists of hierarchically organized areas reciprocally connected via feedforward (FF) and feedback (FB) circuits. Several theories of hierarchical computation ascribe the bulk of the computational work of the cortex to looped FF-FB circuits between pairs of cortical areas. However, whether such corticocortical loops exist remains unclear. In higher mammals, individual FF-projection neurons send afferents almost exclusively to a single higher-level area. However, it is unclear whether FB-projection neurons show similar area-specificity, and whether they influence FF-projection neurons directly or indirectly. Using viral-mediated monosynaptic circuit tracing in macaque primary visual cortex (V1), we show that V1 neurons sending FF projections to area V2 receive monosynaptic FB inputs from V2, but not other V1-projecting areas. We also find monosynaptic FB-to-FB neuron contacts as a second motif of FB connectivity. Our results support the existence of FF-FB loops in primate cortex, and suggest that FB can rapidly and selectively influence the activity of incoming FF signals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.