Evidence map›Paper›PMID 34389674›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Astrocyte-derived neurons provide excitatory input to the adult striatal circuitry.

Matthijs C Dorst, María Díaz-Moreno, David O Dias, Eduardo L Guimarães, Daniel Holl, Jannis Kalkitsas, Gilad Silberberg, Christian Göritz

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 62 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Matthijs C DorstDepartment of Neuroscience, Karolinska Institutet, SE-171 77 Stockholm, Sweden.ORCID 0000-0002-1162-1481
María Díaz-MorenoDepartment of Cell and Molecular Biology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
David O DiasDepartment of Cell and Molecular Biology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.ORCID 0000-0002-2144-6621
Eduardo L GuimarãesDepartment of Cell and Molecular Biology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Daniel HollDepartment of Cell and Molecular Biology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.ORCID 0000-0002-2254-7889
Jannis KalkitsasDepartment of Cell and Molecular Biology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Gilad SilberbergDepartment of Neuroscience, Karolinska Institutet, SE-171 77 Stockholm, Sweden; gilad.silberberg@ki.se christian.goeritz@ki.se.ORCID 0000-0001-9964-505X
Christian GöritzDepartment of Cell and Molecular Biology, Karolinska Institutet, SE-171 77 Stockholm, Sweden; gilad.silberberg@ki.se christian.goeritz@ki.se.
Karolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Astrocytes have emerged as a potential source for new neurons in the adult mammalian brain. In mice, adult striatal neurogenesis can be stimulated by local damage, which recruits striatal astrocytes into a neurogenic program by suppression of active Notch signaling (J. P. Magnusson et al.,

Indexed as

AnimalsAstrocytesCell DifferentiationConnexin 30DeoxyuridineElectrophysiological PhenomenaGABAergic NeuronsGene Expression RegulationGlutamic AcidInterneuronsLuminescent ProteinsMiceMice, TransgenicNeuronsNitric Oxide Synthase Type IRecombination, Genetic5-ethynyl-2'-deoxyuridineConnexin 30DeoxyuridineGjb6 protein, mouseGlutamic AcidLuminescent ProteinsNitric Oxide Synthase Type ITamoxifenastrocyte-derived neurogenesisglutamatergicneuronsstriatum

Identifiers

PMID34389674
PMCPMC8379996
OpenAlexW3189419588

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.