Evidence map›Paper›PMID 34389540›Full record

ArticleScience advances2021

A two-step strategy for delivering particles to targets hidden within microfabricated porous media.

Huanshu Tan, Anirudha Banerjee, Nan Shi, Xiaoyu Tang, Amr Abdel-Fattah, Todd M Squires

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Upper Bounds on the Colloid Separation Efficiency of Diffusiophoresis.Langmuir : the ACS journal of surfaces and colloids · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Data-Driven Intelligent Manipulation of Particles in Microfluidics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huanshu TanDepartment of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA 93106-5080, USA. huanshutan@gmail.com squires@engineering.ucsb.edu.ORCID http://orcid.org/0000-0002-2474-4843
Anirudha BanerjeeDepartment of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA 93106-5080, USA.ORCID http://orcid.org/0000-0001-7715-4161
Nan ShiSaudi Aramco, EXPEC Advanced Research Center, Dhahran 31311, Saudi Arabia.
Xiaoyu TangDepartment of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA 93106-5080, USA.ORCID http://orcid.org/0000-0001-5257-4362
Amr Abdel-FattahSaudi Aramco, EXPEC Advanced Research Center, Dhahran 31311, Saudi Arabia.
Todd M SquiresDepartment of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA 93106-5080, USA. huanshutan@gmail.com squires@engineering.ucsb.edu.ORCID http://orcid.org/0000-0001-6609-9275

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The delivery of small particles into porous environments remains highly challenging because of the low permeability to the fluids that carry these colloids. Even more challenging is that the specific location of targets in the porous environment usually is not known and cannot be determined from the outside. Here, we demonstrate a two-step strategy to deliver suspended colloids to targets that are "hidden" within closed porous media. The first step serves to automatically convert any hidden targets into soluto-inertial "beacons," capable of sustaining long-lived solute outfluxes. The second step introduces the deliverable objects, which are designed to autonomously migrate against the solute fluxes emitted by the targets, thereby following chemical trails that lead to the target. Experimental and theoretical demonstrations of the strategy lay out the design elements required for the solute and the deliverable objects, suggesting routes to delivering colloidal objects to hidden targets in various environments and technologies.

Identifiers

PMID34389540
PMCPMC8363150

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.