SynthesisChest2022
Systematic Review of Ozone Effects on Human Lung Function, 2013 Through 2020.
Synthesis in Chest, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.
- Exposure to long-term ambient air pollution and lung function in adults: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Short-term exposure to heat associated with lower lung function in older adults: analysis of the Lung VITAL cohort.BMJ open respiratory research · 2026Article
- Small airways dysfunction: associated factors, clinical aspects and new perspectives.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Estimating daily ozone levels in urban ambient air.Environmental monitoring and assessment · 2026Article
- Short-term ozone exposure significantly elevates paediatric respiratory disease risk in Foshan, Southern China.BMJ open respiratory research · 2026Article
- Joint impacts of air pollution and healthy lifestyles on kidney function decline: insights from a nationwide cohort study.Renal failure · 2025Article
- Article
- ALX/FPR2 Contributes to Serum Amyloid A-Induced Lung Neutrophil Recruitment Following Acute Ozone Exposure.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Article
- Urban greenspace under a changing climate: Benefit or harm for allergies and respiratory health?Environmental epidemiology (Philadelphia, Pa.) · 2025Review
- Synergistic Toxicity of Fine Particulate Matter and Ozone and Their Underlying Mechanisms.Toxics · 2025Review
- Nutrition, Lifestyle, and Environmental Factors in Lung Homeostasis and Respiratory Health.Nutrients · 2025Review
- Long-Term Exposure to Nitrogen Dioxide and Ozone and Respiratory Health in Children.Annals of the American Thoracic Society · 2025Article
- Neurological Crisis Following Intravenous Ozone Therapy; a Case Report.Archives of academic emergency medicine · 2025Article
- Home and school pollutant exposure, respiratory outcomes, and influence of historical redlining.The Journal of allergy and clinical immunology · 2024Article
- Sex Differences in Impacts of Early Gestational and Peri-Adolescent Ozone Exposure on Lung Development in Rats: Implications for Later Life Disease in Humans.The American journal of pathology · 2024Article
- Outdoor Air Pollution and Pediatric Respiratory Disease.Clinics in chest medicine · 2024Review
- Impact of environmental air pollution on respiratory health and function.Physiological reports · 2024Review
- Continuing benefits of the Montreal Protocol and protection of the stratospheric ozone layer for human health and the environment.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024Article
- Toward Better and Healthier Air Quality: Global PMGlobal challenges (Hoboken, NJ) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundOzone effects on lung function are particularly important to understand in the context of the air pollution-health outcomes epidemiologic literature, given the complex relationships between ozone and other air pollutants with known lung function effects. RESEARCH QUESTION: What has been learned about the association between ozone exposures and lung function from epidemiology studies published from 2013 through 2020? STUDY DESIGN AND
methodsOn March 18, 2018, and September 8, 2020, PubMed was searched using the terms health AND ozone, filtering to articles in English and about humans, from 2013 or later. An additional focused review searching for ozone AND (lung function OR FEV
resultsOf 3,271 articles screened, 53 ultimately met criteria for inclusion. A systematic review with assessment of potential for bias was conducted, but a meta-analysis was not carried out because of differences in exposure duration and outcome quantification. Consistent evidence exists of small decreases in children's lung function, even associated with very low levels of short-term ozone exposure. The effects on adult lung function from exposure to low-level, short-term ozone are less clear, although ozone-associated decrements may occur in the elderly. Finally, long-term ozone exposure decreases both lung function and lung function growth in children, although few new studies have examined long-term ozone and lung function in adults.
interpretationMuch of this literature involves concentrations below the current US Environmental Protection Agency's National Ambient Air Quality Standard of 70 parts per billion over an 8-h averaging time, suggesting that this current standard may not protect children adequately from ozone-related decrements in lung function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.