Evidence map›Paper›PMID 34389284›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Serosurvey of anti-treponema pallidum (syphilis), anti-hepatitis C virus and anti-HIV antibodies in homeless persons of São Paulo city, southeastern Brazil.

Laís Giuliani Felipetto, Pedro Irineu Teider-Junior, Felipe Fortino Verdan da Silva, Anahi Chechia do Couto, Louise Bach Kmetiuk, Camila Marinelli Martins, Leila Sabrina Ullmann, Jorge Timenetsky, Andrea Pires Dos Santos, Alexander Welker Biondo

Open access · goldAbstract read
In one paragraph

Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. One health approach on serosurvey of anti-One health (Amsterdam, Netherlands) · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Laís Giuliani FelipettoFederal University of Paraná, Department of Veterinary Medicine, College of Veterinary Science, Curitiba, PR, Brazil.
Pedro Irineu Teider-JuniorFederal University of Paraná, Department of Veterinary Medicine, College of Veterinary Science, Curitiba, PR, Brazil.
Felipe Fortino Verdan da SilvaFederal University of Paraná, Clinics Hospital, Clinical Analysis Laboratory Unit, Curitiba, PR, Brazil.
Anahi Chechia do CoutoFederal University of Paraná, Department of Cellular and Molecular Biology, College of Cellular and Molecular Biology, Curitiba, PR, Brazil.
Louise Bach KmetiukFederal University of Paraná, Department of Cellular and Molecular Biology, College of Cellular and Molecular Biology, Curitiba, PR, Brazil.
Camila Marinelli MartinsState University of Ponta Grossa, Department of Nursing and Public Health, Ponta Grossa, PR, Brazil.
Leila Sabrina UllmannSão Paulo State University, Institute of Biotechnology, Botucatu, São Paulo, Brazil.
Jorge TimenetskyUniversity of São Paulo, Department of Medical Microbiology, São Paulo, Brazil.
Andrea Pires Dos SantosPurdue University, Department of Comparative Pathobiology, West Lafayette, IN, USA.
Alexander Welker BiondoFederal University of Paraná, Department of Veterinary Medicine, College of Veterinary Science, Curitiba, PR, Brazil; Federal University of Paraná, Department of Cellular and Molecular Biology, College of Cellular and Molecular Biology, Curitiba, PR, Brazil; Federal University of Paraná, Department of Veterinary Medicine, Curitiba, PR, Brazil. Electronic address: abiondo@ufpr.br.
Universidade Federal do Paraná · BRHospital de Clínicas Universidade Federal do Paraná · BRPurdue University West Lafayette · USUniversidade de São Paulo · BRUniversidade Estadual de Ponta Grossa · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homeless persons have been considered as one of the most susceptible populations to sexually transmitted infections. In Brazil, these population experienced an increase of 140% from 2012 to 2020. Accordingly, the present study aimed to assess the seroprevalence of anti-Treponema pallidum, anti-HCV, anti-HIV antibodies, and the risk factors associated with homeless persons in a daytime attendance shelter of São Paulo city during the syphilis epidemic in Brazil. Blood samples of 116 volunteers and epidemiological data were conveniently collected in the shelter from June through August 2018. Detection of syphilis, HCV, and HIV antibodies was performed by chemiluminescent microparticle immunoassay (CMIA). CMIA-reagent samples for anti-T. pallidum antibodies were confirmed by Venereal Disease Research Laboratory (VDRL) non-treponemal test. VDRL non-reagent samples were confirmed by treponemal rapid immunochromatographic test. A rapid immunoblot assay confirmed seropositivity to HIV. Overall, anti-T. pallidum antibodies were observed in 29/116 (25.0%), anti-HCV antibodies in 4/116 (3.4%), and anti-HIV antibodies in 2/116 (1.7%) individuals, both co-infected with anti-T. pallidum antibodies. Associated risk factors for syphilis in homeless persons were being born or previously living in another city (p = 0.043) and becoming homeless due to family conflicts (p = 0.035). Besides homeless vulnerability, worldwide shortage of benzathine penicillin supply and increasing of syphilis testing access through rapid testing in primary health care services may have also impacted disease spreading at the time. The prevalence of syphilis found herein is the highest worldwide to date in this population.

Indexed as

Hepatitis CHIV-1HIV InfectionsIll-Housed PersonsSyphilisBrazilHepacivirusHIV AntibodiesHumansSeroepidemiologic StudiesTreponema pallidumHIV AntibodiesHCVHIVHomelessSyphilisVulnerability

Identifiers

PMID34389284
PMCPMC9392160
OpenAlexW3188939241

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.