Evidence map›Paper›PMID 34389028›Full record

SynthesisJournal of orthopaedic surgery and research2021

Orthopedic management of myelomeningocele with a multidisciplinary approach: a systematic review of the literature.

Parnian Shobeiri, Ana Presedo, Amirali Karimi, Sara Momtazmanesh, Fardis Vosoughi, Mohammad Hossein Nabian

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Sexual Dysfunction and Lower Urinary Tract Dysfunction in Adults With Spina Bifida.International journal of urology : official journal of the Japanese Urological Association · 2026
    Observational
  2. Article
  3. Article
  4. Neurogenic Bladder in Children with Myelomeningocele.Diseases (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Parnian ShobeiriSchool of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Ana Presedo *Department of Pediatric Orthopedics, Hôpital Robert Debre, Paris, France.
Amirali Karimi *School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Sara MomtazmaneshSchool of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Fardis VosoughiDepartment of Orthopedic and trauma surgery, Shariati Hospital and School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Mohammad Hossein NabianDepartment of Orthopedic and trauma surgery, Shariati Hospital and School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran. Dr.nabian@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMyelomeningocele (MMC) is the most common and severe form of spina bifida and imposes a significant burden on patients and the healthcare system. Recently, the multidisciplinary management of MMC has become popular. Herein, we aimed to review the orthopedic management, outcomes, and complications of the of patients with MMC eyeing a multidisciplinary approach.

methodsWe searched PubMed and EMBASE to find relevant studies published before August 2020. All studies that included clinical management of MMC patients and published earlier than 2000 were considered for review on the condition that they reported at least one orthopedic intervention and the rate of complications. We excluded review articles, case reports, case series, letters, commentaries, editorials, and conference abstracts. The primary and secondary goals of our review were to report the outcomes and complication rates of multidisciplinary management for MMC patients.

resultsTwenty-six studies included data for the management of 229,791 patients with MMC and were selected. Sixteen studies reported multidisciplinary management in addition to orthopedic management. From those, 11 (42.31%) included urologic management, 13 (50%) neurosurgical management, 11 (42.31%) neurologic management, and 5 (19.23%) gastrointestinal management. All studies included postnatal operations and related management. No randomized clinical trial was found in our search.

conclusionOrthopedic approaches play a key role in MMC management by alleviating spinal deformities, particularly scoliosis, and hip, foot, and ankle complications. However, the most appropriate management, whether surgical or non-surgical, may vary for different patients, given disease severity and the age of patients.

Indexed as

MeningomyeloceleOrthopedicsScoliosisHumansCommunicationInterdisciplinaryMeningomyeloceleOrthopedicsSpinal dysraphism

Identifiers

PMID34389028
PMCPMC8361640

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.