Evidence map›Paper›PMID 34389025›Full record

ArticleJournal of orthopaedic surgery and research2021

Disc measurement and nucleus calibration in a smoothened lumbar model increases the accuracy and efficiency of in-silico study.

Jingchi Li, Chen Xu, Xiaoyu Zhang, Zhipeng Xi, Shenglu Sun, Ke Zhang, Xiaoyang Fang, Lin Xie, Yang Liu, Yueming Song

Abstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Disc degeneration did not lead to an increased incidence of adjacent vertebral fractures in wedge-type OVCF patients.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jingchi Li *Department of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital/West China School of Medicine for Sichuan University, Chengdu, 610041, China.
Chen Xu *Department of Spine Surgery, Changzheng Hospital Affiliated to the Naval Medical University, Shanghai, 200041, China.
Xiaoyu Zhang *Department of Spine Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine for Nanjing University of Chinese Medicine, Nanjing, 210028, China.
Zhipeng XiDepartment of Spine Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine for Nanjing University of Chinese Medicine, Nanjing, 210028, China.
Shenglu SunDepartment of Imaging, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine for Nanjing University of Chinese Medicine, Nanjing, 210028, Jiangsu, China.
Ke ZhangDepartment of Spine Surgery, Changzheng Hospital Affiliated to the Naval Medical University, Shanghai, 200041, China.
Xiaoyang FangDepartment of Spine Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine for Nanjing University of Chinese Medicine, Nanjing, 210028, China.
Lin XieDepartment of Spine Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine for Nanjing University of Chinese Medicine, Nanjing, 210028, China. xielin6508@163.com.ORCID http://orcid.org/0000-0002-2538-347X
Yang LiuDepartment of Spine Surgery, Changzheng Hospital Affiliated to the Naval Medical University, Shanghai, 200041, China. lyspinesurgery@163.com.
Yueming SongDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital/West China School of Medicine for Sichuan University, Chengdu, 610041, China. sym_cd@163.com.

Funding

Foundation for leading talent in traditional Chinese medicine of Jiangsu province (2018SLJ0210)Key project of jiangsu province social development (BE2019765)
6 · The paper itself

Abstract

backgroundsFinite element analysis (FEA) is an important tool during the spinal biomechanical study. Irregular surfaces in FEA models directly reconstructed based on imaging data may increase the computational burden and decrease the computational credibility. Definitions of the relative nucleus position and its cross-sectional area ratio do not conform to a uniform standard in FEA.

methodsTo increase the accuracy and efficiency of FEA, nucleus position and cross-sectional area ratio were measured from imaging data. A FEA model with smoothened surfaces was constructed using measured values. Nucleus position was calibrated by estimating the differences in the range of motion (RoM) between the FEA model and that of an in-vitro study. Then, the differences were re-estimated by comparing the RoM, the intradiscal pressure, the facet contact force, and the disc compression to validate the measured and calibrated indicators. The computational time in different models was also recorded to evaluate the efficiency.

resultsComputational results indicated that 99% of accuracy was attained when measured and calibrated indicators were set in the FEA model, with a model validation of greater than 90% attained under almost all of the loading conditions. Computational time decreased by around 70% in the fitted model with smoothened surfaces compared with that of the reconstructed model.

conclusionsThe computational accuracy and efficiency of in-silico study can be improved in the lumbar FEA model constructed using smoothened surfaces with measured and calibrated relative nucleus position and its cross-sectional area ratio.

Indexed as

Intervertebral DiscLumbar VertebraeBiomechanical PhenomenaCalibrationFinite Element AnalysisLumbosacral RegionRange of Motion, ArticularCross-sectional area ratioFinite element analysisModel calibrationRelative nucleus positionSmoothened surfaces

Identifiers

PMID34389025
PMCPMC8362282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.