Evidence map›Paper›PMID 34388999›Full record

ArticleBMC urology2021

No staghorn calculi and none/mild hydronephrosis may be risk factors for severe bleeding complications after percutaneous nephrolithotomy.

Xue Dong, Dongnv Wang, Huangqi Zhang, Shuzong You, Wenting Pan, Peipei Pang, Chaoqian Chen, Hongjie Hu, Wenbin Ji

Open access · goldAbstract read
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Article in BMC urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Xue DongDepartment of Radiology, Taizhou Hospital, Zhejiang University, Taizhou, 318000, Zhejiang, China.
Dongnv WangDepartment of Radiology, Taizhou Hospital, Zhejiang University, Taizhou, 318000, Zhejiang, China.
Huangqi ZhangDepartment of Radiology, Taizhou Hospital, Zhejiang University, Taizhou, 318000, Zhejiang, China.
Shuzong YouDepartment of Radiology, Taizhou Hospital, Zhejiang University, Taizhou, 318000, Zhejiang, China.
Wenting PanDepartment of Radiology, Taizhou Hospital, Zhejiang University, Taizhou, 318000, Zhejiang, China.
Peipei PangDepartment of Pharmaceuticals Diagnosis, GE Healthcare, Hangzhou, China.
Chaoqian ChenDepartment of Urology, Taizhou Hospital of Zhejiang Province, Taizhou, 318000, Zhejiang, China.
Hongjie HuDepartment of Radiology, School of Medicine, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, 310023, Zhejiang, China. hongjiehu@zju.edu.cn.
Wenbin JiDepartment of Radiology, Taizhou Hospital, Zhejiang University, Taizhou, 318000, Zhejiang, China. wb.j@163.com.
Zhejiang Taizhou Hospital · CNWenzhou Medical University · CNSir Run Run Shaw Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo explore the risk factors for severe bleeding complications after percutaneous nephrolithotomy (PCNL) according to the modified Clavien scoring system.

methodsWe retrospectively analysed 2981 patients who received percutaneous nephrolithotomies from January 2014 to December 2020. Study inclusion criteria were PCNL and postoperative mild or severe renal haemorrhage in accordance with the modified Clavien scoring system. Mild bleeding complications included Clavien 2, while severe bleeding complications were greater than Clavien 3a. It has a good prognosis and is more likely to be underestimated and ignored in retrospective studies in bleeding complications classified by Clavien 1, so no analysis about these was conducted in this study. Clinical features, medical comorbidities and perioperative characteristics were analysed. Chi-square, independent t tests, Pearson's correlation, Fisher exact tests, Mann-Whitney and multivariate logistic regression were used as appropriate.

resultsOf the 2981 patients 70 (2.3%), met study inclusion criteria, consisting of 51 men and 19 women, 48 patients had severe bleeding complications. The remaining 22 patients had mild bleeding. Patients with postoperative severe bleeding complications were more likely to have no or slight degree of hydronephrosis and have no staghorn calculi on univariate analysis (p < 0.05). Staghorn calculi (OR, 95% CI, p value 0.218, 0.068-0.700, 0.010) and hydronephrosis (OR, 95% CI, p value 0.271, 0.083-0.887, 0.031) were independent predictors for severe bleeding via multivariate logistic regression analysis. Other factors, such as history of PCNL, multiple kidney stones, site of puncture calyx and mean corrected intraoperative haemoglobin drop were not related to postoperative severe bleedings.

conclusionsThe absence of staghorn calculi and a no or mild hydronephrosis were related to an increased risk of post-percutaneous nephrolithotomy severe bleeding complications.

Indexed as

Staghorn CalculiAgedFemaleHumansHydronephrosisKidney CalculiMaleMiddle AgedNephrolithotomy, PercutaneousPostoperative HemorrhageRetrospective StudiesRisk FactorsComputed tomographyHydronephrosisPercutaneous nephrolithotomyPostoperative complicationsStaghorn calculiThe modified Clavien scoring

Identifiers

PMID34388999
PMCPMC8361647
OpenAlexW3188559952

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.