Evidence map›Paper›PMID 34388462›Full record

ArticleComputers in biology and medicine2021

Deep learning and lung ultrasound for Covid-19 pneumonia detection and severity classification.

Marco La Salvia, Gianmarco Secco, Emanuele Torti, Giordana Florimbi, Luca Guido, Paolo Lago, Francesco Salinaro, Stefano Perlini, Francesco Leporati

Open access · greenAbstract read
In one paragraph

Article in Computers in biology and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 84 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Marco La SalviaUniversity of Pavia, Department of Electrical, Computer and Biomedical Engineering, Via Ferrata 5, Pavia I, 27100, Italy. Electronic address: marco.lasalvia01@universitadipavia.it.
Gianmarco SeccoFondazione IRCCS Policlinico San Matteo, Emergency Department, Viale Camillo Golgi 19, Pavia I, 27100, Italy.
Emanuele TortiUniversity of Pavia, Department of Electrical, Computer and Biomedical Engineering, Via Ferrata 5, Pavia I, 27100, Italy.
Giordana FlorimbiUniversity of Pavia, Department of Electrical, Computer and Biomedical Engineering, Via Ferrata 5, Pavia I, 27100, Italy.
Luca GuidoUniversity of Pavia, Department of Electrical, Computer and Biomedical Engineering, Via Ferrata 5, Pavia I, 27100, Italy.
Paolo LagoFondazione IRCCS Policlinico San Matteo, Emergency Department, Viale Camillo Golgi 19, Pavia I, 27100, Italy.
Francesco SalinaroFondazione IRCCS Policlinico San Matteo, Emergency Department, Viale Camillo Golgi 19, Pavia I, 27100, Italy.
Stefano PerliniFondazione IRCCS Policlinico San Matteo, Emergency Department, Viale Camillo Golgi 19, Pavia I, 27100, Italy.
Francesco LeporatiUniversity of Pavia, Department of Electrical, Computer and Biomedical Engineering, Via Ferrata 5, Pavia I, 27100, Italy.
University of Pavia · ITPoliclinico San Matteo Fondazione · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Covid-19 European outbreak in February 2020 has challenged the world's health systems, eliciting an urgent need for effective and highly reliable diagnostic instruments to help medical personnel. Deep learning (DL) has been demonstrated to be useful for diagnosis using both computed tomography (CT) scans and chest X-rays (CXR), whereby the former typically yields more accurate results. However, the pivoting function of a CT scan during the pandemic presents several drawbacks, including high cost and cross-contamination problems. Radiation-free lung ultrasound (LUS) imaging, which requires high expertise and is thus being underutilised, has demonstrated a strong correlation with CT scan results and a high reliability in pneumonia detection even in the early stages. In this study, we developed a system based on modern DL methodologies in close collaboration with Fondazione IRCCS Policlinico San Matteo's Emergency Department (ED) of Pavia. Using a reliable dataset comprising ultrasound clips originating from linear and convex probes in 2908 frames from 450 hospitalised patients, we conducted an investigation into detecting Covid-19 patterns and ranking them considering two severity scales. This study differs from other research projects by its novel approach involving four and seven classes. Patients admitted to the ED underwent 12 LUS examinations in different chest parts, each evaluated according to standardised severity scales. We adopted residual convolutional neural networks (CNNs), transfer learning, and data augmentation techniques. Hence, employing methodological hyperparameter tuning, we produced state-of-the-art results meeting F1 score levels, averaged over the number of classes considered, exceeding 98%, and thereby manifesting stable measurements over precision and recall.

Indexed as

COVID-19Deep LearningPneumoniaHumansLungReproducibility of ResultsSARS-CoV-2Deep learningLung ultrasoundLUS ScoreSARS-CoV-2

Identifiers

PMID34388462
PMCPMC8349313
OpenAlexW3190790668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.