Evidence map›Paper›PMID 34388155›Full record

ArticlePloS one2021

Are men who have sex with men at higher risk for HIV in Latin America more aware of PrEP?

Ryan D Assaf, Kelika A Konda, Thiago S Torres, E Hamid Vega-Ramirez, Oliver A Elorreaga, Dulce Diaz-Sosa, Steven D Diaz, Cristina Pimenta, Rebeca Robles, Maria Elena Medina-Mora and 3 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Behavioral and structural drivers of HIV in men who have sex with men in Belize: a mixed-methods study.Revista panamericana de salud publica = Pan American journal of public health · 2026
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  5. Review
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  8. Assessing the Underestimation of HIV Risk Infection among Young Men Who Have Sex with Men in Argentina.International journal of environmental research and public health · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Ryan D AssafUniversity of California Los Angeles, Los Angeles, CA, United States of America.ORCID 0000-0002-6651-1765
Kelika A KondaCentro de Investigación Interdisciplinaria en Sexualidad Sida y Sociedad, UPCH, Lima, Peru.
Thiago S TorresInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz (INI-Fiocruz), Rio de Janeiro, Brazil.
E Hamid Vega-RamirezInstituto Nacional de Psiquiatria Ramon de la Fuente Muñiz, Mexico City, Mexico.
Oliver A ElorreagaCentro de Investigación Interdisciplinaria en Sexualidad Sida y Sociedad, UPCH, Lima, Peru.ORCID 0000-0003-0181-5378
Dulce Diaz-SosaInstituto Nacional de Psiquiatria Ramon de la Fuente Muñiz, Mexico City, Mexico.
Steven D DiazUnited Nations Population Fund (UNFPA Mexico) of Mexico City, Mexico City, Mexico.
Cristina PimentaMinistério da Saúde Brazil, Brasília, Brazil.
Rebeca RoblesInstituto Nacional de Psiquiatria Ramon de la Fuente Muñiz, Mexico City, Mexico.
Maria Elena Medina-MoraInstituto Nacional de Psiquiatria Ramon de la Fuente Muñiz, Mexico City, Mexico.
Beatriz GrinsztejnInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz (INI-Fiocruz), Rio de Janeiro, Brazil.
Carlos CaceresCentro de Investigación Interdisciplinaria en Sexualidad Sida y Sociedad, UPCH, Lima, Peru.
Valdilea G VelosoInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz (INI-Fiocruz), Rio de Janeiro, Brazil.
Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz · MXFundação Oswaldo Cruz · BRMinistério da Saúde · BRUniversity of California, Los Angeles · US

Funding

The FIOCRUZ Therapeutic and Prevention HIV/AIDS Clinical Trials Unit (FioTrials)UM1AI069476 · NIAID · FUNDACAO OSWALDO CRUZ · PI BEATRIZ GRINSZTEJN · 2012 to 2026
$26.3M
The FIOCRUZ Therapeutic and Prevention HIV/AIDS Clinical Trials Unit (FioTrials)U01AI069476 · NIAID · FUNDACAO OSWALDO CRUZ · PI GRINSZTEJN, BEATRIZ · 2008 to 2011
$14.0M
NIAID NIH HHS U01 AI069476NIAID NIH HHS UM1 AI069476
6 · The paper itself

Abstract

introductionPrEP awareness in Latin America has been poorly characterized, with studies in Brazil, Mexico, and Peru highlighting awareness of 65% among gay, bisexual and other men who have sex with men (MSM). We assessed the association between higher risk of HIV infection, indicative of PrEP eligibility, and PrEP awareness among MSM from these countries.

methodsThis was a secondary analysis of a web-based survey advertised on social media platforms from March-June 2018 in Brazil, Mexico and Peru. Eligible individuals were cisgender MSM, ≥18 years old, HIV negative or of unknown status, who lived in these countries, and provided informed consent. Higher risk of HIV infection was defined as having 10 or more points in the HIV Risk Index for MSM (HIRI-MSM). We used multivariable Poisson regression models to calculate adjusted prevalence ratios (aPR) testing the association between higher risk for HIV and PrEP awareness.

resultsAfter exclusions, 19,457 MSM were included in this analysis. In Brazil, 53.8% were classified as higher risk for HIV, 51.9% in Mexico, and 54.2% in Peru. Higher risk for HIV was minimally associated with PrEP awareness among those in Brazil (aPR 1.04, 95% CI 1.01, 1.06), but no such association was observed in Mexico or Peru. Having more than a high school education, high income, daily use of geosocial networking (GSN) applications, and substance use were associated with PrEP awareness.

conclusionHigher risk of HIV infection was associated with increased PrEP awareness in Brazil. However, this association was weak indicating that PrEP awareness could be strengthened with further prevention efforts. In the remaining countries, results were non-conclusive between risk and awareness. Interventions to increase PrEP awareness are paramount to increase PrEP willingness and uptake and in turn prevent new HIV infections. Social media platforms could play an important role to achieve this goal.

Indexed as

Health Knowledge, Attitudes, PracticePatient Acceptance of Health CareAdministration, OralAdolescentAdultAnti-HIV AgentsHIVHIV InfectionsHomosexuality, MaleHumansLatin AmericaMalePre-Exposure ProphylaxisSafe SexSurveys and QuestionnairesYoung AdultAnti-HIV Agents

Identifiers

PMID34388155
PMCPMC8362965
OpenAlexW3193022625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.