ArticlePloS one2021
Discrepancies between clinical diagnosis and hospital autopsy: A comparative retrospective analysis of 1,112 cases.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Accelerating Proficiency in Minimally Invasive Autopsy for Infectious Disease Diagnosis and Research: A Strategic Framework.Revista da Sociedade Brasileira de Medicina Tropical · 2026Observational
- Major discrepancy between clinical and autopsy diagnosis: a descriptive single-center analysis and its implications for the South African public health system.Frontiers in medicine · 2026Article
- Variance in intraindividual stability of vitreous humor for thanatochemistry.International journal of legal medicine · 2025Article
- Autopsy rates and diagnostic errors in a Swiss community hospital: a ten-year retrospective analysis.Virchows Archiv : an international journal of pathology · 2025Article
- Clinicopathological Observations in Acute Stroke Patients Treated with Intravenous Thrombolysis.Journal of clinical medicine · 2024Article
- Comparison of Ante-Mortem Clinical Diagnosis and Final Autopsy Diagnosis: Experience from a Single Academic Centre in Pretoria, South Africa.Diseases (Basel, Switzerland) · 2024Article
- Diagnostic uncertainty of steroid-modified Marburg's variant of multiple sclerosis even at autopsy: A case suggesting lymphoma and related myelin loss.eNeurologicalSci · 2024Article
- Assessment of misdiagnosis in small animal intensive care patients using the Modified Goldman criteria.The veterinary quarterly · 2023Article
- Lesions and pathogens found in pigs that died during the nursery period in five Danish farms.Porcine health management · 2023Article
- The autopsy is not dead: ongoing relevance of the autopsy.Autopsy & case reports · 2023Article
- Autopsy in the era of advanced cardiovascular imaging.European heart journal · 2022Review
- A Comprehensive Review of Pathological Examination in Forensic Medicine: Past, Present, and Future.Cureus · 2022Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe aim of this study was to compare discrepancies between diagnosed and autopsied causes of death in 1,112 hospital autopsies and to determine the factors causing this discrepancies.
methods1,112 hospital autopsies between 2010 and 2013 were retrospectively studied. Ante-mortem diagnoses were compared to causes of death as determined by autopsy. Clinical diagnoses were extracted from the autopsy request form, and post-mortem diagnoses were assessed from respective autopsy reports. Variables, such as sex, age, Body Mass Index, category of disease, duration of hospital stay and new-borns were studied in comparison to discrepancy. P-values were derived from the Mann-Whitney U test for the constant features and chi-2 test, p-values < 0,05 were considered significant.
results73.9% (n = 822) patients showed no discrepancy between autopsy and clinical diagnosis. The duration of hospitalisation (6 vs. 9 days) and diseases of the cardiovascular system (61.7%) had a significant impact on discrepancies.
conclusionAge, cardiovascular diseases and duration of hospital stay significantly affect discrepancies in ante- and post-mortem diagnoses.
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